Peer-reviewed research
Every peer-reviewed study we cite across the compounds we track, gathered in one place and linked straight to its PubMed record. We summarize the literature and point you to it — we don't interpret it. Where a study or an FDA label published a dose, we report it with the source named. Nothing here is an endorsement or an efficacy or safety claim, and none of it is a recommendation to use anything. Everything is research use only.
How a review has to be sourced before it can ship — the citation, numeric-claim, evidence-label and language checks that fail the build rather than the reader. And kept separately from the literature: what regulators actually published, filed as dated primary-source records.
New · Field Notes Where peptide science meets the real world → Reported explainers on regulation, testing, and emerging research—including our veterinary peptide investigation.Evidence reviews
Neutral, fact-checked summaries of the peer-reviewed literature per compound — every claim cited, every source linked. Research use only.
- What the research says about vesugen Preclinical only
A neutral summary of the peer-reviewed literature on vesugen, a synthetic Lys-Glu-Asp tripeptide bioregulator studied almost entirely by a single research lineage in animal and in-vitro models, with one small uncontrolled human observational study and no controlled human trials. Research use only.
- What the research says about prostamax Preclinical only
A neutral summary of the peer-reviewed literature on prostamax, a synthetic Lys-Glu-Asp-Pro short-peptide bioregulator studied almost entirely by a single research lineage in animal and in-vitro models, including cultures of ex-vivo human lymphocytes from elderly donors. There are no controlled human trials. Research use only.
- What the research says about cardiogen Preclinical only
A neutral summary of the peer-reviewed literature on cardiogen, a synthetic short-peptide bioregulator studied almost entirely by a single research lineage in animal and in-vitro models, including ex-vivo human-cell cultures. There are no controlled human trials. Research use only.
- What the research says about VIP Moderate evidence
A neutral summary of the peer-reviewed literature on vasoactive intestinal peptide (VIP), a 28-amino-acid endogenous neuropeptide that acts as a potent vasodilator and immune modulator, with human evidence concentrated in physiology rather than therapeutic trials. Research use only.
- What the research says about vilon Preclinical only
A neutral summary of the peer-reviewed literature on Vilon, a synthetic Lys-Glu dipeptide bioregulator studied almost entirely by a single research lineage in animal, in-vitro, and human-cell-culture models, with no controlled human clinical trials. Research use only.
- What the research says about tirzepatide Strong evidence
A neutral summary of the peer-reviewed literature on tirzepatide, a dual GIP/GLP-1 receptor agonist studied in multiple phase 3 randomized trials for type 2 diabetes and obesity. Research use only.
- What the research says about thymulin Limited evidence
A neutral summary of the peer-reviewed literature on thymulin, a zinc-dependent thymic peptide studied mostly in cell and animal models of immune, neuroendocrine, and inflammatory signaling, with human data limited to observational measurements of endogenous thymulin activity. Research use only.
- What the research says about thymosin alpha-1 Strong evidence
A neutral summary of the peer-reviewed literature on thymosin alpha-1, an immune-modulating peptide studied in randomized trials and meta-analyses in specific patient populations such as sepsis, severe pancreatitis, COVID-19, COPD exacerbation, and chronic viral hepatitis. Research use only.
- What the research says about thymogen Limited evidence
A neutral summary of the peer-reviewed literature on thymogen, the synthetic Glu-Trp dipeptide immunomodulator, studied mostly in animal and cell models with human data limited to older, largely uncontrolled clinical reports and a single older placebo-controlled surgical trial. Research use only.
- What the research says about thymalin Limited evidence
A neutral summary of the peer-reviewed literature on thymalin, a thymus-derived peptide preparation studied mostly in cell and animal models of immune signaling, with human data limited to older, uncontrolled clinical reports and recent case series. Research use only.
- What the research says about tesofensine Limited evidence
A neutral summary of the peer-reviewed literature on tesofensine, an oral triple monoamine reuptake inhibitor studied for weight reduction, whose pivotal obesity trial later drew a journal Expression of Concern. Research use only.
- What the research says about tesamorelin Strong evidence
A neutral summary of the peer-reviewed literature on tesamorelin, a growth-hormone-releasing hormone analogue studied in randomized trials and pooled meta-analysis for HIV-associated abdominal fat. Research use only.
- What the research says about teriparatide Strong evidence
A neutral summary of the peer-reviewed literature on teriparatide, a parathyroid-hormone analogue studied in randomized trials and meta-analyses as an anabolic osteoporosis therapy. Research use only.
- What the research says about TB-500 and thymosin β4 Preclinical only
A neutral summary of the peer-reviewed literature behind TB-500, a peptide related to thymosin β4 studied almost entirely in animal and in-vitro models. No controlled human trials exist. Research use only.
- What the research says about survodutide Moderate evidence
A neutral summary of the peer-reviewed literature on survodutide (BI 456906), an investigational glucagon-receptor / GLP-1-receptor dual agonist studied in phase 2 trials for obesity, type 2 diabetes, and MASH. Research use only.
- What the research says about SS-31 (elamipretide) Moderate evidence
A neutral summary of the peer-reviewed literature on SS-31 (elamipretide), a mitochondria-targeting tetrapeptide that gained a narrow accelerated approval for Barth syndrome after mixed results in randomized trials. Research use only.
- What the research says about SLU-PP-332 Preclinical only
A neutral summary of the peer-reviewed literature on SLU-PP-332, a synthetic pan-agonist of the estrogen-related receptors (ERRs) studied as an exercise mimetic entirely in cell and animal models. Research use only.
- What the research says about sermorelin Limited evidence
A neutral summary of the peer-reviewed literature on sermorelin, a growth-hormone-releasing hormone analogue historically used as a diagnostic agent and studied in growth-hormone-deficient children. The modern research base is thin. Research use only.
- What the research says about Semax Limited evidence
A neutral summary of the peer-reviewed literature on Semax, a synthetic analogue of ACTH(4-10) studied mainly in animal and cell models, with a small human literature concentrated in Russian-language neurology journals. Research use only.
- What the research says about semaglutide Strong evidence
A neutral summary of the peer-reviewed literature on semaglutide, a GLP-1 receptor agonist studied in phase 3 randomized trials and pooled meta-analysis for weight management and type 2 diabetes. Research use only.
- What the research says about Selank Limited evidence
A neutral summary of the peer-reviewed literature on Selank, a synthetic anxiolytic heptapeptide studied mainly in animal models, with a few small human studies concentrated in Russian-language psychiatry journals. Research use only.
- What the research says about PT-141 (bremelanotide) Moderate evidence
A neutral summary of the peer-reviewed literature on PT-141 (bremelanotide), a melanocortin-receptor agonist studied in phase 3 randomized trials for hypoactive sexual desire disorder in women, where the measured effects are statistically significant but modest and debated. Research use only.
- What the research says about PNC-27 Preclinical only
A neutral summary of the peer-reviewed literature on PNC-27, a p53/HDM-2-derived membrane-active peptide studied only in cancer-cell cultures and mouse tumor models. There are no human trials. Research use only.
- What the research says about pinealon Limited evidence
A neutral summary of the peer-reviewed literature on pinealon, a synthetic Glu-Asp-Arg short peptide bioregulator studied mostly in cell-culture and animal models of neural tissue, with human data limited to small uncontrolled observational reports. Research use only.
- What the research says about Pancragen Limited evidence
A neutral summary of the peer-reviewed literature on Pancragen, a short synthetic peptide bioregulator studied by a single research group in rat, monkey, and cell-culture models of glucose tolerance and pancreatic cell differentiation, with only small human data. Research use only.
- What the research says about oxytocin Moderate evidence
A neutral summary of the peer-reviewed literature on oxytocin, an established obstetric hormone whose newer intranasal use for social, psychiatric, and metabolic effects remains an active and unsettled research area. Research use only.
- What the research says about orforglipron Strong evidence
A neutral summary of the peer-reviewed literature on orforglipron, an oral small-molecule (nonpeptide) GLP-1 receptor agonist studied in a series of manufacturer-sponsored randomized trials for weight reduction and glycemic control. Research use only.
- What the research says about NAD+ Limited evidence
A neutral summary of the peer-reviewed literature on NAD+, a coenzyme central to metabolism whose age-related decline is studied mostly in preclinical models. Human trials largely test oral precursors, not injected NAD+, and report limited efficacy. Research use only.
- What the research says about MOTS-c Preclinical only
A neutral summary of the peer-reviewed literature on MOTS-c, a mitochondrial-derived peptide studied almost entirely in cell and animal models of metabolism and aging. No controlled human trials exist. Research use only.
- What the research says about MK-677 (ibutamoren) Moderate evidence
A neutral summary of the peer-reviewed literature on MK-677 (ibutamoren mesylate), an orally active growth-hormone secretagogue studied in multiple randomized human trials that raised IGF-1 but largely missed their clinical endpoints. Research use only.
- What the research says about MGF Preclinical only
A neutral summary of the peer-reviewed literature on mechano-growth factor (MGF), a splice variant of IGF-1 studied in cell and animal models of muscle, cartilage, and neural repair. No controlled human trials, and a notable independent replication failure. Research use only.
- What the research says about methylene blue Limited evidence
A neutral summary of the peer-reviewed literature on methylene blue, an old synthetic dye with established emergency uses and largely preclinical claims around cognition and aging. Research use only.
- What the research says about Melanotan II Preclinical only
A neutral summary of the peer-reviewed literature on Melanotan II, a melanocortin-receptor agonist used illicitly for tanning. There are no controlled human efficacy trials, and the human record is dominated by adverse-event case reports. Research use only.
- What the research says about Melanotan I (afamelanotide) Moderate evidence
A neutral summary of the peer-reviewed literature on Melanotan I, the alpha-MSH analogue that, as the pharmaceutical afamelanotide, was studied in randomized trials and approved for a rare light-intolerance disorder, while its popular tanning use remains unregulated and untested. Research use only.
- What the research says about mazdutide Strong evidence
A neutral summary of the peer-reviewed literature on mazdutide (IBI362 / LY3305677), a glucagon-receptor / GLP-1-receptor dual agonist studied in multiple randomized trials and approved in China for weight management and type 2 diabetes. Research use only.
- What the research says about Matrixyl (palmitoyl pentapeptide) Limited evidence
A neutral summary of the peer-reviewed literature on Matrixyl, a palmitoyl-pentapeptide cosmetic ingredient studied in fibroblast collagen assays and small topical trials. Research use only.
- What the research says about LL-37 Preclinical only
A neutral summary of the peer-reviewed literature on LL-37, the only human cathelicidin antimicrobial peptide, studied largely as native host-defense biology and in preclinical models, with context-dependent and sometimes harmful effects. Research use only.
- What the research says about livagen Preclinical only
A neutral summary of the peer-reviewed literature on Livagen, a synthetic Lys-Glu-Asp-Ala tetrapeptide bioregulator studied almost entirely by a single research lineage in human-cell-culture, in-vitro, and animal models, with no controlled human clinical trials. Research use only.
- What the research says about L-carnitine and acetyl-L-carnitine Moderate evidence
A neutral summary of the peer-reviewed literature on L-carnitine and its acetyl ester (ALCAR), studied in human trials across neuropathy, mood, and cognition with mixed results. Research use only.
- What the research says about KPV Preclinical only
A neutral summary of the peer-reviewed literature on KPV (lysine-proline-valine), the C-terminal tripeptide of alpha-MSH studied for anti-inflammatory and antimicrobial effects almost entirely in cell and animal models. Research use only.
- What the research says about kisspeptin Limited evidence
A neutral summary of the peer-reviewed literature on kisspeptin, a hypothalamic neuropeptide studied extensively in human experimental-medicine physiology of the reproductive axis, with fewer large therapeutic trials. Research use only.
- What the research says about ipamorelin Limited evidence
A neutral summary of the peer-reviewed literature on ipamorelin, a selective growth-hormone secretagogue studied mainly in animal and in-vitro models, with only small early human trials. Research use only.
- What the research says about IGF-1 LR3 Preclinical only
A neutral summary of the peer-reviewed literature on IGF-1 LR3 (Long R3 IGF-1), an insulin-like growth factor-1 analog used mainly as a laboratory research reagent and studied only in animal and cell models. No controlled human trials of the analog exist. Research use only.
- What the research says about humanin Limited evidence
A neutral summary of the peer-reviewed literature on humanin, a small mitochondrial-derived peptide studied for cytoprotection in cell and animal models, with human evidence limited to observational and genetic associations. Research use only.
- What the research says about hexarelin Moderate evidence
A neutral summary of the peer-reviewed literature on hexarelin, a synthetic growth-hormone-releasing peptide studied mainly in short human neuroendocrine experiments and in animal cardiovascular models. Research use only.
- What the research says about HCG Moderate evidence
A neutral summary of the peer-reviewed literature on human chorionic gonadotropin (hCG), a glycoprotein hormone that acts through the LH/CG receptor, best known in pregnancy and reproductive endocrinology. Research use only.
- What the research says about gonadorelin Moderate evidence
A neutral summary of the peer-reviewed literature on gonadorelin, synthetic gonadotropin-releasing hormone (GnRH), whose effect on the reproductive axis depends critically on whether it is delivered in pulses or continuously. Research use only.
- What the research says about glutathione Strong evidence
A neutral summary of the peer-reviewed literature on supplemental glutathione, studied in randomized trials and systematic reviews mostly for skin lightening plus a few metabolic and pediatric outcomes, where oral bioavailability and clinical benefit remain debated. Research use only.
- What the research says about GHRP-6 Moderate evidence
A neutral summary of the peer-reviewed literature on GHRP-6, a synthetic growth-hormone-releasing hexapeptide studied in short human growth-hormone-stimulation and diagnostic trials. Research use only.
- What the research says about GHRP-2 Moderate evidence
A neutral summary of the peer-reviewed literature on GHRP-2 (pralmorelin), a synthetic growth-hormone-releasing peptide studied in short human growth-hormone-secretion and endocrine-physiology trials. Research use only.
- What the research says about GHK-Cu Preclinical only
A neutral summary of the peer-reviewed literature on GHK-Cu, a copper-binding tripeptide studied largely in cell, animal, and topical-cosmetic models of skin and tissue repair. Controlled injectable human trials are essentially absent. Research use only.
- What the research says about FOXO4-DRI Preclinical only
A neutral summary of the peer-reviewed literature on FOXO4-DRI, a synthetic senolytic peptide designed to disrupt the FOXO4-p53 interaction and trigger death of senescent cells. All evidence to date is in cells and animals. Research use only.
- What the research says about follistatin Preclinical only
A neutral summary of the peer-reviewed literature on follistatin, an activin- and myostatin-binding protein studied in animal models of muscle growth and, in humans, mostly as a circulating metabolic biomarker. No controlled human administration trials. Research use only.
- What the research says about Epithalon Limited evidence
A neutral summary of the peer-reviewed literature on Epithalon (Epitalon), a synthetic pineal tetrapeptide studied mainly in animal and cell models of aging, with a small human literature dominated by a single research group. Research use only.
- What the research says about DSIP Limited evidence
A neutral summary of the peer-reviewed literature on DSIP (delta sleep-inducing peptide), a nine-amino-acid peptide studied mainly in animal models, with a small human literature that is old and inconclusive. Research use only.
- What the research says about dihexa Preclinical only
A neutral summary of the peer-reviewed literature on dihexa, an angiotensin-IV-derived peptide studied as a procognitive, synaptogenic agent in animal models. Research use only.
- What the research says about cortagen Preclinical only
A neutral summary of the peer-reviewed literature on cortagen, a synthetic brain-cortex-derived tetrapeptide bioregulator studied only in animal and in-vitro models, including ex-vivo human-cell cultures. There are no controlled human trials. Research use only.
- What the research says about CJC-1295 Limited evidence
A neutral summary of the peer-reviewed literature on CJC-1295, a long-acting growth-hormone-releasing hormone analogue studied in small early human pharmacology trials and animal models. No clinical outcome trials exist. Research use only.
- What the research says about cerebrolysin Conflicting evidence
A neutral summary of the peer-reviewed literature on cerebrolysin, a porcine-brain-derived peptide preparation studied in stroke and dementia trials with conflicting results. Research use only.
- What the research says about cagrilintide Moderate evidence
A neutral summary of the peer-reviewed literature on cagrilintide, an investigational long-acting amylin analogue studied in an early-phase human trial for weight management. Research use only.
- What the research says about bronchogen Preclinical only
A neutral summary of the peer-reviewed literature on bronchogen, a synthetic Ala-Asp-Glu-Leu short peptide bioregulator studied only in animal lung models and in-vitro cell and DNA assays. There are no controlled human trials. Research use only.
- What the research says about BAM15 Preclinical only
A neutral summary of the peer-reviewed literature on BAM15, a mitochondrial-uncoupler small molecule studied in cell and animal models of obesity and metabolic disease. Research use only.
- What the research says about argireline (acetyl hexapeptide-8) Moderate evidence
A neutral summary of the peer-reviewed literature on argireline (acetyl hexapeptide-8), a topical cosmetic peptide studied in small randomized anti-wrinkle trials. Research use only.
- Are research peptides safe? What the evidence does and doesn't show Limited evidence
A neutral, cited look at what "safe" can and cannot mean for research peptides. The published record ranges from large human trials for a few compounds to animal-only data for many. Not medical advice. Research use only.
- What the research says about ARA-290 (cibinetide) Moderate evidence
A neutral summary of the peer-reviewed literature on ARA-290 (cibinetide), a non-erythropoietic erythropoietin-derived peptide studied in small phase 2 trials of sarcoidosis-associated small-fiber neuropathy and other conditions. Research use only.
- What the research says about AOD-9604 Limited evidence
A neutral summary of the peer-reviewed literature on AOD-9604, a C-terminal fragment of human growth hormone studied as a lipolytic anti-obesity candidate. The human evidence is older and limited, and much of the recent literature is anti-doping detection methodology rather than efficacy. Research use only.
- What the research says about AICAR Preclinical only
A neutral summary of the peer-reviewed literature on AICAR, an AMPK-activating small molecule studied as an experimental exercise-mimetic in cell and animal models. Research use only.
- What the research says about adipotide Preclinical only
A neutral summary of the peer-reviewed literature on adipotide, a fat-targeting pro-apoptotic peptidomimetic studied in obese monkeys and rodent models. Research use only.
- What the research says about retatrutide Moderate evidence
A neutral summary of the peer-reviewed literature on retatrutide, an experimental triple-hormone-receptor agonist studied in early-phase human trials for obesity. Research use only.
- What the research says about BPC-157 and tissue repair Preclinical only
A neutral summary of the peer-reviewed literature on BPC-157, a peptide studied almost entirely in animal and in-vitro models for tissue repair. No controlled human trials exist. Research use only.
Every study we cite
72 studies across 24 compounds
BPC-157 3 studies
Retatrutide 3 studies
- Triple-Hormone-Receptor Agonist Retatrutide for Obesity - A Phase 2 Trial
- Triple hormone receptor agonist retatrutide for metabolic dysfunction-associated steatotic liver disease: a randomized phase 2a trial
- Effects of once-weekly subcutaneous retatrutide on weight and metabolic markers: A systematic review and meta-analysis of randomized controlled trials
Tirzepatide 3 studies
- Efficacy and safety of a novel dual GIP and GLP-1 receptor agonist tirzepatide in patients with type 2 diabetes (SURPASS-1): a double-blind, randomised, phase 3 trial
- Tirzepatide once weekly for the treatment of obesity in people with type 2 diabetes (SURMOUNT-2): a double-blind, randomised, multicentre, placebo-controlled, phase 3 trial
- Tirzepatide as Compared with Semaglutide for the Treatment of Obesity
Semaglutide 3 studies
- Semaglutide 2·4 mg once a week in adults with overweight or obesity, and type 2 diabetes (STEP 2): a randomised, double-blind, double-dummy, placebo-controlled, phase 3 trial
- Efficacy and Safety of Semaglutide for Weight Loss in Obesity Without Diabetes: A Systematic Review and Meta-Analysis
- Safety of Semaglutide
TB-500 3 studies
Tesamorelin 3 studies
Cagrilintide 3 studies
- Once-weekly cagrilintide for weight management in people with overweight and obesity: a multicentre, randomised, double-blind, placebo-controlled and active-controlled, dose-finding phase 2 trial
- Coadministered Cagrilintide and Semaglutide in Adults with Overweight or Obesity
- Development of Cagrilintide, a Long-Acting Amylin Analogue
Ipamorelin 3 studies
CJC-1295 3 studies
- Prolonged stimulation of growth hormone (GH) and insulin-like growth factor I secretion by CJC-1295, a long-acting analog of GH-releasing hormone, in healthy adults
- Once-daily administration of CJC-1295, a long-acting growth hormone-releasing hormone (GHRH) analog, normalizes growth in the GHRH knockout mouse
- Netnography of Female Use of the Synthetic Growth Hormone CJC-1295: Pulses and Potions
Sermorelin 3 studies
- Sermorelin: a better approach to management of adult-onset growth hormone insufficiency?
- Sermorelin: a review of its use in the diagnosis and treatment of children with idiopathic growth hormone deficiency
- Beyond the androgen receptor: the role of growth hormone secretagogues in the modern management of body composition in hypogonadal males
NAD+ 3 studies
MOTS-c 3 studies
GHK-Cu 3 studies
Melanotan II 3 studies
PT-141 3 studies
Selank 3 studies
- Selank Administration Affects the Expression of Some Genes Involved in GABAergic Neurotransmission
- Selank, Peptide Analogue of Tuftsin, Protects Against Ethanol-Induced Memory Impairment by Regulating of BDNF Content in the Hippocampus and Prefrontal Cortex in Rats
- The Influence of Selank on the Level of Cytokines Under the Conditions of "Social" Stress
Semax 3 studies
- Semax, an ACTH(4-10) analogue with nootropic properties, activates dopaminergic and serotoninergic brain systems in rodents
- Semax and Pro-Gly-Pro activate the transcription of neurotrophins and their receptor genes after cerebral ischemia
- Semax peptide targets the μ opioid receptor gene Oprm1 to promote deubiquitination and functional recovery after spinal cord injury in female mice
Kisspeptin 3 studies
Epithalon 3 studies
AOD-9604 3 studies
Glutathione 3 studies
- Supplementing Glycine and N-Acetylcysteine (GlyNAC) in Older Adults Improves Glutathione Deficiency, Oxidative Stress, Mitochondrial Dysfunction, Inflammation, Physical Function, and Aging Hallmarks: A Randomized Clinical Trial
- Randomized controlled trial of oral glutathione supplementation on body stores of glutathione
- GlyNAC Supplementation Improves Glutathione Deficiency, Oxidative Stress, Mitochondrial Dysfunction, Inflammation, Aging Hallmarks, Metabolic Defects, Muscle Strength, Cognitive Decline, and Body Composition: Implications for Healthy Aging
Thymosin Alpha-1 3 studies
DSIP 3 studies
IGF-1 LR3 3 studies
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A representative set of studies for each compound, linked straight to PubMed — not an endorsement or a claim that any result applies to human use. Read them and judge for yourself. pepmg sells nothing and gives no medical or human-use guidance. Everything here is research use only.