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DSIPSleep peptide

Compound dossier · evidence, sources, and live market

DSIP

Sleep peptide Limited evidence 3 cited studies 76 live vendors

DSIP (delta sleep-inducing peptide) is a short endogenous nonapeptide first isolated from cerebral venous blood, widely catalogued as a neuropeptide research term. In laboratory settings it is studied for its interactions with sleep-related and neuroendocrine signaling in animal and in-vitro models. This index tracks research-use-only (RUO) vendor pricing for DSIP so researchers can compare cost across suppliers.

Evidence brief

DSIP (delta sleep-inducing peptide) is a nine-amino-acid peptide first isolated from rabbit blood and studied mainly in animal models of sleep, pain, and stress.

cheapest (first-party)
$2.96/mg
highest
$12.48/mg
first-party vendors
76
Fair-price band · 76 first-party vendors · $/mg
median $6.00
$2.96cheapest $12.48highest
Comparing vendors on DSIP can save up to $9.52/mg — the cheapest tracked is $2.96/mg, the priciest $12.48/mg.

first-party prices captured 37m ago

Compare by exact vialThe small sealed glass container a compound ships in. size: 5mg (47 vendors)10mg (37 vendors)15mg (4 vendors)

email only when a vendor actually lowers a DSIP price — set a $/mg to only hear when it crosses your number · one-click stop
▸ Regulatory statusUSnot approvedEUnot approvedUKnot approved

Not approved by the FDA, EMA, or MHRA. FDA considered emideltide (DSIP)-related substances for the 503A Bulks List at its July 24, 2026 PCAC meeting.Research use only — not medical advice.

Source: FDA Pharmacy Compounding Advisory Committee · July 23–24, 2026checked 2026-07-26

DSIP · market statistics 76 sources tracked

These figures are what pepmg still publishes about price: the floor, the middle, the spread and how many sources we track, computed from listings we captured first-party and refreshed on the same schedule as always. We no longer publish the individual listings or the sellers behind them.

lowest tracked $2.96/mg
median $6.00/mg
highest tracked $12.48/mg
spread 4.2×
Lowest tracked $/mg, 38 days 8% cheaper over the period
07/01 · $3.20 low $2.94 · high $3.20 08/16 · $2.96

Computed from 93 in-stock listings across 76 sources we captured first-party, with bulk vials, blends and statistical outliers excluded so the figures compare like with like. The spread is the highest tracked price divided by the lowest — how much the same milligram varies depending on where you look. The chart is the daily minimum; days we did not capture are left out rather than filled in.

COACertificate of Analysis: a lab report stating a batch's measured identity and purity. availability: 66 of 76 sources selling DSIP publish a COA — 38 with at least one certificate you can open at the testing lab. What a COA proves →
Independent lab tests: Finnrick's batch purity results for DSIP → — third-party testing data, independent of every vendor and of pepmg.
Blends & stacks: 2 first-party multi-peptide products contain DSIP , priced $315.00–$405.00 per unit. We don't rank these by $/mgPrice divided by the milligrams of active compound — the like-for-like way to compare cost across different vial sizes. — a per-milligram figure across different peptides isn't comparable — so they stay out of the figures above.
Research articles about DSIP All research →
Peer-reviewed research · DSIPsource: PubMed
  1. Delta-sleep-inducing peptide (DSIP): a review PubMed ↗
    ReviewhumanNeuroscience and biobehavioral reviews · 1984 · PMID 6145137

    Since the turn of the century, it has been postulated that humoral factors induce sleep. Many compounds were proposed as sleep-factors, but only two of the sleep-peptides have been purified to homogeneity and characterized, so far. One of…

  2. Delta sleep-inducing peptide (DSIP): a still unresolved riddle PubMed ↗
    ReviewhumanJournal of neurochemistry · 2006 · PMID 16539679

    Delta sleep-inducing peptide (DSIP) was isolated from rabbit cerebral venous blood by Schoenenberger-Monnier group from Basel in 1977 and initially regarded as a candidate sleep-promoting factor. However, the link between DSIP and sleep…

  3. Delta Sleep-Inducing Peptide Recovers Motor Function in SD Rats after Focal Stroke PubMed ↗
    StudyanimalMolecules · 2021 · PMID 34500605

    Background and Objectives: Mutual effect of the preliminary and therapeutic intranasal treatment of SD rats with DSIP (8 days) on the outcome of focal stroke, induced with intraluminal middle cerebral occlusion (MCAO), was investigated.…

A few representative studies, each summarized on this site with the PubMed record linked beside it — not an endorsement or a claim that any result applies to human use. Read them and judge for yourself. Everything here is research use only.

Browse all peer-reviewed research →

Why compare $/mg for DSIP?

Per-mg prices for DSIP vary because vendors differ in synthesis scale, stated purity, fill quantity per vial, and lot testing overhead. Comparing normalized $/mg across suppliers helps a researcher gauge whether a listing is competitively priced rather than reflecting a smaller fill or lighter documentation.

Reading the COA

For DSIP, confirm identity by mass spectrometry against the expected monoisotopic mass of the nonapeptide sequence (Trp-Ala-Gly-Gly-Asp-Ala-Ser-Gly-Glu), and check that reported HPLC purity meets a stated threshold (commonly 98%+ for research material). Watch for common synthesis-related impurities such as truncated or deletion sequences and residual TFA counterions; a COA should show the HPLC chromatogram and MS trace, not just a summary percentage.

FAQ

How is lyophilized DSIP typically stored in a lab?
As a lyophilized powder, DSIP is generally kept sealed and protected from moisture and light, stored cold (often refrigerated short-term or frozen for longer periods) per the vendor's stated conditions. It is a research chemical, and any storage guidance on the COA or product page refers to preserving material integrity for laboratory work, not to human use.
What is a COA and what should I check for on a DSIP certificate?
A Certificate of Analysis (COA) is the vendor's lot-specific quality document. For DSIP, check that it identifies the peptide by mass spectrometry (matching the expected mass), reports HPLC purity against a stated threshold, lists the lot/batch number, and ideally includes the actual chromatogram and MS data so identity and purity can be independently assessed.
Why do per-mg prices for DSIP differ so much between vendors?
Differences come from synthesis batch size, stated purity grade, the amount of peptide per vial, counterion content, and the depth of analytical testing documented. A lower headline price can reflect a smaller fill or less rigorous testing, which is why normalizing to $/mg and reading the COA together gives a clearer comparison.

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→ Reconstitution calculator for DSIP research math.
All products listed are sold by third-party vendors for laboratory and research use only (RUO). Where an FDA label or a peer-reviewed study has published a dose, pepmg reports it with the source named, because that is safer than guessing. It is a report, not medical advice and not a recommendation to use anything. pepmg sells nothing and ships nothing. Listings are price-tracking data, not endorsements.