Compound dossier · evidence, sources, and live market
IGF-1 LR3
Growth factor Preclinical only 3 cited studies 43 live vendors
IGF-1 LR3 (Long-R3 insulin-like growth factor-1) is an 83-amino-acid analog of human IGF-1, modified by an arginine substitution at position 3 and a 13-residue N-terminal extension that reduce its binding to IGF-binding proteins. It is a research peptide studied in laboratory and cell-culture models of growth-factor signaling, cell proliferation, and receptor biology. This index tracks research-use-only (RUO) vendor pricing for IGF-1 LR3 so researchers can compare cost across suppliers.
Evidence brief
IGF-1 LR3 (Long R3 IGF-1) is a modified insulin-like growth factor-1 analog with reduced binding to the IGF-binding proteins, used chiefly as a laboratory research reagent.
first-party prices captured 37m ago
Compare by exact vialThe small sealed glass container a compound ships in. size: 1mg (42 vendors)
A laboratory reagent — not an approved medicine anywhere; research use only.Research use only — not medical advice.
These figures are what pepmg still publishes about price: the floor, the middle, the spread and how many sources we track, computed from listings we captured first-party and refreshed on the same schedule as always. We no longer publish the individual listings or the sellers behind them.
Computed from 44 in-stock listings across 43 sources we captured first-party, with bulk vials, blends and statistical outliers excluded so the figures compare like with like. The spread is the highest tracked price divided by the lowest — how much the same milligram varies depending on where you look. The chart is the daily minimum; days we did not capture are left out rather than filled in.
- What the research says about IGF-1 LR3 Preclinical only
IGF-1 LR3 (Long R3 IGF-1) is a modified insulin-like growth factor-1 analog with reduced binding to the IGF-binding proteins, used chiefly as a laboratory research reagent.
Read the full review →
- IGF-1 LR3 does not promote growth in late-gestation growth-restricted fetal sheep PubMed ↗
Insulin-like growth factor-1 (IGF-1) and insulin are important fetal anabolic hormones. Complications of pregnancy, such as placental insufficiency, can lead to fetal growth restriction (FGR) with low-circulating IGF-1 and insulin…
- Sheep recombinant IGF-1 promotes organ-specific growth in fetal sheep PubMed ↗
IGF-1 is a critical fetal growth-promoting hormone. Experimental infusion of an IGF-1 analog, human recombinant LR3 IGF-1, into late gestation fetal sheep increased fetal organ growth and skeletal muscle myoblast proliferation. However,…
- Recombinant expression of IGF-1 and LR3 IGF-1 fused with xylanase in Pichia pastoris PubMed ↗
Insulin-like growth factor-1 (IGF-1) is a pleiotropic protein hormone and has become an attractive therapeutic target because of its multiple roles in various physiological processes, including growth, development, and metabolism. However,…
A few representative studies, each summarized on this site with the PubMed record linked beside it — not an endorsement or a claim that any result applies to human use. Read them and judge for yourself. Everything here is research use only.
▸ Why compare $/mg for IGF-1 LR3?
Per-mg pricing for IGF-1 LR3 varies widely because vendors differ in synthesis or recombinant expression method, stated purity, vial fill size, and lot testing rigor. Comparing normalized $/mg across suppliers helps a researcher weigh cost against documented quality rather than paying a premium for equivalent material.
▸ Reading the COA
For IGF-1 LR3, confirm identity by mass spectrometry against the expected mass of roughly 9.1 kDa for the 83-residue analog, and check that the sequence reflects the Arg3 substitution and the N-terminal extension rather than native IGF-1. Look for an HPLC purity figure (commonly >=95-98%) and scrutinize the impurity profile for truncated or misfolded species and deamidation products, since incorrect disulfide folding can yield material that fails functional or identity verification despite having the same nominal mass. A legitimate COA is lot-specific and should also state endotoxin and, ideally, residual solvent or counterion content.
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