Tiers name what a vendor publishes, not a verdict on any product's purity or quality.
Lab-verifiable COAs: certificates that open on the testing lab's own site (the seal's ring shows what share of them do).
Third-party COAs: certificates attributed to a third-party lab, which may be hosted only on the vendor's site.
Tiers follow the Vendor Score (90+ and 80–89), which is 87% COA evidence; the numeral in each seal is that score.
Affiliate relationships never affect tiers, selection or order. How the Vendor Score works
Thymosin Alpha-1 (Tα1) is a 28-amino-acid synthetic peptide originally characterized from the thymic protein prothymosin alpha. It appears in laboratory research as a reference peptide studied in immunology-related contexts. It is chemically and structurally distinct from TB-500 (a thymosin beta-4 fragment) despite the shared "thymosin" naming. This index tracks research-use-only (RUO) vendor pricing for Thymosin Alpha-1 to help researchers compare cost across suppliers.
Evidence brief
Thymosin alpha-1 is a synthetic immune-modulating peptide (studied and marketed in some countries as the drug thymalfasin) evaluated in randomized trials and meta-analyses, almost entirely in specific patient populations rather than healthy people.
Compare by exact vialThe small sealed glass container a compound ships in.The small sealed glass container a compound ships in. size:
5mg (15 vendors)10mg (45 vendors)
Approved as a medicine (thymalfasin, Zadaxin) in about 30 countries including China; not approved by the FDA, EMA, or MHRA.Research use only — not medical advice.
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Thymosin Alpha-1 · all tracked vendors · all tracked peptide listings, including out-of-stock products. Prices and stock reflect the last check. Non-comparable products do not enter market rankings. Trust scores measure published evidence, not product safety.
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COACertificate of Analysis: a lab report stating a batch's measured identity and purity.Certificate of Analysis: a lab report stating a batch's measured identity and purity. availability: 64 of 69 tracked sources for Thymosin Alpha-1 publish a COA
— 46 with at least one certificate you can open at the testing lab: Modern Research Peptides (276 at the lab), Iron Aminos (250 at the lab), Eternal Peptides (141 at the lab), EZ Peptides (136 at the lab), Peptide Partners (133 at the lab), Ameano Peptides (108 at the lab), Blank Peptides (101 at the lab), Oros Research (96 at the lab), True Research Labs (96 at the lab), RUO.bio (91 at the lab), Nationwide Peptides (88 at the lab), Nexaph (88 at the lab), and 52 more — every one of them is a linked row in the table above. What a COA proves →
Multi-peptide products (e.g. BPC-157 + TB-500). We don't rank these by $/mgPrice divided by the milligrams of active compound — the like-for-like way to compare cost across different vial sizes.Price divided by the milligrams of active compound — the like-for-like way to compare cost across different vial sizes. — a per-milligram figure across different peptides isn't comparable — so they're listed separately by total price and kept out of the headline index above.
● Research articles about Thymosin Alpha-1All research →
Thymosin alpha-1 is a synthetic immune-modulating peptide (studied and marketed in some countries as the drug thymalfasin) evaluated in randomized trials and meta-analyses, almost entirely in specific patient populations rather than healthy people.
Source-linked reference figures with the population and study context alongside each amount. Study arms are not a starting dose, titration schedule, or personal treatment plan. Label records refer to the named approved medicine, not vendor products.
Dose administered in a multicentre randomised double-blind placebo-controlled trial (human, patients with predicted severe acute necrotising pancreatitis)
1.6 mg every 12 h for the first 7 days and 1.6 mg once a day for the subsequent 7 days
human · patients with predicted severe acute necrotising pancreatitis · multicentre randomised double-blind placebo-controlled trial · Route reported: subcutaneous
Research use only — this reports what an FDA label or a peer-reviewed study published, tied to its species and study context. It is not medical advice, not a recommendation to use, and no dose here is generated by pepmg. Any dosing decision is for a qualified professional. Animal-study amounts do not establish a human dose.
Reconstitution calculator → · Converts your entered quantities; it does not select a dose or establish suitability for use.
● Peer-reviewed research · Thymosin Alpha-1source: PubMed
To evaluate whether the immunomodulatory drug thymosin α1 reduces mortality in adults with sepsis.
Multicentre, double blinded, placebo controlled phase 3 trial.
22 centres in China, September 2016 to December 2020.
1106 adults aged…
StudyhumanExpert opinion on biological therapy · 2015 · PMID 25640173
Stimulating a successful host immune response may be a promising helpful therapy to achieve elimination of hepatitis B virus (HBV) infection in chronic hepatitis B (CHB). Thymosin α-1 (Tα-1), as an immunomodulatory agent, can enhance…
ReviewhumanInternational journal of molecular sciences · 2025 · PMID 41373628
Aging is characterized by immune decline, mainly due to thymic involution-the age-related shrinkage of the thymus gland. This leads to reduced T-cell production, chronic inflammation, and increased susceptibility to age-related diseases.…
A few representative studies, each summarized on this site with the PubMed record linked beside it — not an endorsement or a claim that any result applies to human use. Read them and judge for yourself. Everything here is research use only.
Per-milligram prices for Thymosin Alpha-1 vary across vendors because of differences in synthesis scale, stated HPLC purity, fill quantity per vial, and how each supplier documents identity and lot testing. Comparing normalized $/mg lets a researcher weigh a lower headline price against purity grade and vial size so the true cost of usable material is clear.
▸ Reading the COA
For Thymosin Alpha-1, confirm identity by mass spectrometry against the expected monoisotopic/average mass for the 28-residue sequence (roughly 3108 Da for the acetylated form), since it is easily confused on a label with TB-500/thymosin beta-4 fragments. Look for HPLC purity stated at 98%+ with the chromatogram attached, and treat missing or generic COAs as unverified. Common quality flags include deletion/truncation sequences and residual TFA counter-ion, so check that the report references this specific peptide's lot number rather than a boilerplate template.
▸ FAQ
How is lyophilized Thymosin Alpha-1 typically stored as a research material?
As a general storage note for research material, lyophilized peptides like Thymosin Alpha-1 are commonly kept sealed, desiccated, and frozen (often -20°C or colder) for long-term storage, protected from light, moisture, and repeated temperature cycling. Dry powder is generally more stable than reconstituted material. This is storage information only and not use guidance.
What is a COA and what should I check on one for Thymosin Alpha-1?
A Certificate of Analysis (COA) is a lot-specific document reporting a material's identity and purity. For Thymosin Alpha-1, check that mass spectrometry confirms the expected mass for the 28-residue sequence (not a TB-500 fragment), that HPLC purity is stated with an attached chromatogram, and that the lot number on the COA matches the vial you received.
Why does the per-mg price of Thymosin Alpha-1 differ so much between vendors?
Differences come from synthesis batch size, stated purity grade, the amount of peptide per vial, and the depth of analytical documentation. A vial priced low overall may carry a higher $/mg once fill quantity is normalized, while higher-purity, fully-documented lots often cost more per mg, which is why normalized comparison is useful.
All products listed are sold by third-party vendors for laboratory and research use only (RUO). Where an FDA label or a peer-reviewed study has published a dose, pepmg reports it with the source named, because that is safer than guessing. It is a report, not medical advice and not a recommendation to use anything. pepmg sells nothing and ships nothing. Listings are price-tracking data, not endorsements.
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