Compound dossier · evidence, sources, and live market
Thymosin Alpha-1
Immune peptide Strong evidence 3 cited studies 62 live vendors
Thymosin Alpha-1 (Tα1) is a 28-amino-acid synthetic peptide originally characterized from the thymic protein prothymosin alpha. It appears in laboratory research as a reference peptide studied in immunology-related contexts. It is chemically and structurally distinct from TB-500 (a thymosin beta-4 fragment) despite the shared "thymosin" naming. This index tracks research-use-only (RUO) vendor pricing for Thymosin Alpha-1 to help researchers compare cost across suppliers.
Evidence brief
Thymosin alpha-1 is a synthetic immune-modulating peptide (studied and marketed in some countries as the drug thymalfasin) evaluated in randomized trials and meta-analyses, almost entirely in specific patient populations rather than healthy people.
first-party prices captured 37m ago
Compare by exact vialThe small sealed glass container a compound ships in. size: 5mg (19 vendors)10mg (50 vendors)
Approved as a medicine (thymalfasin, Zadaxin) in about 30 countries including China; not approved by the FDA, EMA, or MHRA.Research use only — not medical advice.
These figures are what pepmg still publishes about price: the floor, the middle, the spread and how many sources we track, computed from listings we captured first-party and refreshed on the same schedule as always. We no longer publish the individual listings or the sellers behind them.
Computed from 71 in-stock listings across 62 sources we captured first-party, with bulk vials, blends and statistical outliers excluded so the figures compare like with like. The spread is the highest tracked price divided by the lowest — how much the same milligram varies depending on where you look. The chart is the daily minimum; days we did not capture are left out rather than filled in.
- What the research says about thymosin alpha-1 Strong evidence
Thymosin alpha-1 is a synthetic immune-modulating peptide (studied and marketed in some countries as the drug thymalfasin) evaluated in randomized trials and meta-analyses, almost entirely in specific patient populations rather than healthy people.
Read the full review →
- The efficacy and safety of thymosin α1 for sepsis (TESTS): multicentre, double blinded, randomised, placebo controlled, phase 3 trial PubMed ↗
To evaluate whether the immunomodulatory drug thymosin α1 reduces mortality in adults with sepsis. Multicentre, double blinded, placebo controlled phase 3 trial. 22 centres in China, September 2016 to December 2020. 1106 adults aged…
- Thymosin alpha-1 treatment in chronic hepatitis B PubMed ↗
Stimulating a successful host immune response may be a promising helpful therapy to achieve elimination of hepatitis B virus (HBV) infection in chronic hepatitis B (CHB). Thymosin α-1 (Tα-1), as an immunomodulatory agent, can enhance…
- Aging and Thymosin Alpha-1 PubMed ↗
Aging is characterized by immune decline, mainly due to thymic involution-the age-related shrinkage of the thymus gland. This leads to reduced T-cell production, chronic inflammation, and increased susceptibility to age-related diseases.…
A few representative studies, each summarized on this site with the PubMed record linked beside it — not an endorsement or a claim that any result applies to human use. Read them and judge for yourself. Everything here is research use only.
▸ Why compare $/mg for Thymosin Alpha-1?
Per-milligram prices for Thymosin Alpha-1 vary across vendors because of differences in synthesis scale, stated HPLC purity, fill quantity per vial, and how each supplier documents identity and lot testing. Comparing normalized $/mg lets a researcher weigh a lower headline price against purity grade and vial size so the true cost of usable material is clear.
▸ Reading the COA
For Thymosin Alpha-1, confirm identity by mass spectrometry against the expected monoisotopic/average mass for the 28-residue sequence (roughly 3108 Da for the acetylated form), since it is easily confused on a label with TB-500/thymosin beta-4 fragments. Look for HPLC purity stated at 98%+ with the chromatogram attached, and treat missing or generic COAs as unverified. Common quality flags include deletion/truncation sequences and residual TFA counter-ion, so check that the report references this specific peptide's lot number rather than a boilerplate template.
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