pepmg_
● MELANOTAN IIMelanocortin peptide

Compound dossier · evidence, sources, and live market

Melanotan II

Melanocortin peptide Preclinical only 3 cited studies 70 live vendors

Melanotan II (MT-2) is a synthetic cyclic heptapeptide analog of alpha-melanocyte-stimulating hormone (α-MSH). In laboratory research it is described as a non-selective agonist studied at melanocortin receptors. It is one of the most-searched non-GLP research peptides and is supplied strictly for research use only, not for human or veterinary use. This index tracks per-milligram pricing for Melanotan II across research-use-only (RUO) vendors.

Evidence brief

Melanotan II is a non-selective melanocortin-receptor agonist marketed illicitly to darken skin; it has no controlled human efficacy trials in the peer-reviewed literature.

read the evidence review → inspect cited studies
cheapest (first-party)
$2.11/mg
highest
$8.00/mg
first-party vendors
70
Fair-price band · 70 first-party vendors · $/mg
median $3.70
$2.11cheapest $8.00highest
Comparing vendors on Melanotan II can save up to $5.89/mg — the cheapest tracked is $2.11/mg, the priciest $8.00/mg.

first-party prices captured 37m ago

Compare by exact vialThe small sealed glass container a compound ships in. size: 10mg (69 vendors)

email only when a vendor actually lowers a Melanotan II price — set a $/mg to only hear when it crosses your number · one-click stop
▸ Regulatory statusUSnot approvedEUnot approvedUKnot approved

Not approved anywhere. The UK MHRA and other regulators have issued public warnings against its use.Research use only — not medical advice.

● Melanotan II · market statistics 70 sources tracked

These figures are what pepmg still publishes about price: the floor, the middle, the spread and how many sources we track, computed from listings we captured first-party and refreshed on the same schedule as always. We no longer publish the individual listings or the sellers behind them.

lowest tracked $2.11/mg
median $3.70/mg
highest tracked $8.00/mg
spread 3.8×
Lowest tracked $/mg, 38 days 8% cheaper over the period
07/01 · $2.30 low $2.10 · high $2.30 08/16 · $2.11

Computed from 72 in-stock listings across 70 sources we captured first-party, with bulk vials, blends and statistical outliers excluded so the figures compare like with like. The spread is the highest tracked price divided by the lowest — how much the same milligram varies depending on where you look. The chart is the daily minimum; days we did not capture are left out rather than filled in.

COACertificate of Analysis: a lab report stating a batch's measured identity and purity. availability: 61 of 70 sources selling Melanotan II publish a COA — 32 with at least one certificate you can open at the testing lab. What a COA proves →
Blends & stacks: 1 first-party multi-peptide product contains Melanotan II , priced $261.00–$261.00 per unit. We don't rank these by $/mgPrice divided by the milligrams of active compound — the like-for-like way to compare cost across different vial sizes. — a per-milligram figure across different peptides isn't comparable — so they stay out of the figures above.
● Research articles about Melanotan II All research →
● Peer-reviewed research · Melanotan IIsource: PubMed
  1. Melanotan-II reverses memory impairment induced by a short-term HF diet PubMed ↗
    StudyanimalBiomedicine & pharmacotherapy = Biomedecine & pharmacotherapie · 2023 · PMID 37478579

    A high-fat (HF) diet has been shown to increase the risk of neurological impairments and neurodegenerative disorders. The melanotropins used in this study have been associated with diet-related disorders; however, there is an absence of…

  2. Melanotan-associated melanoma PubMed ↗
    ObservationalhumanThe British journal of dermatology · 2011 · PMID 21564053
  3. Melanotan II: a possible cause of renal infarction: review of the literature and case report PubMed ↗
    ReviewhumanCEN case reports · 2020 · PMID 31953620

    Renal infarction is an uncommon condition resulting from an acute disruption of renal blood flow and it is potentially life-threatening disease. The cause and outcome of renal infarction is not well established and is frequently…

A few representative studies, each summarized on this site with the PubMed record linked beside it — not an endorsement or a claim that any result applies to human use. Read them and judge for yourself. Everything here is research use only.

Browse all peer-reviewed research →

▸ Why compare $/mg for Melanotan II?

Per-mg prices for Melanotan II vary widely because vendors differ in synthesis scale, stated HPLC purity, vial fill size (commonly 10 mg), and how testing and shipping overhead are amortized into the unit price. Comparing normalized $/mg across vendors lets a researcher weigh cost against documented purity rather than headline vial prices.

▸ Reading the COA

For Melanotan II, confirm identity by mass spectrometry against the expected monoisotopic mass (~1024 Da for the cyclic heptapeptide, C50H69N15O9) and check that HPLC purity is reported at 98%+ with a dated, batch-specific chromatogram. Watch for linear (non-cyclized) precursor, deletion/truncation sequences, and acetate/TFA counter-ion content that can inflate net peptide mass; the COA lot number should match the vial label. A COA verifies the identity and purity of the material, not any biological outcome.

▸ FAQ

How should lyophilized Melanotan II be stored in a lab setting?
As a lyophilized powder, Melanotan II is generally stored sealed and protected from light, moisture, and heat, and is typically kept frozen for longer-term storage per the vendor's stated conditions. In solution, peptides of this type are generally less stable than the dry powder and degrade faster; researchers should follow the supplier's documented storage guidance for the specific lot. This is storage information for research material only and is not human-use guidance.
What is a COA and what should I check for on a Melanotan II certificate?
A Certificate of Analysis (COA) is a batch-specific document reporting the analytical testing done on a given lot. For Melanotan II, verify the lot number matches the vial, that identity is confirmed by mass spectrometry against the expected mass, and that HPLC purity (typically 98%+) is shown with a dated chromatogram. A COA verifies the identity and purity of the material, not any biological outcome.
Why do per-mg prices for Melanotan II differ so much between vendors?
Differences come from synthesis and purification scale, stated purity grade, vial fill size, counter-ion content affecting net peptide mass, and whether third-party testing and shipping are bundled into the unit cost. Normalizing to $/mg makes these otherwise hidden differences comparable across research-use-only suppliers.

▸ Same cluster

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→ Reconstitution calculator for Melanotan II research math.
All products listed are sold by third-party vendors for laboratory and research use only (RUO). Where an FDA label or a peer-reviewed study has published a dose, pepmg reports it with the source named, because that is safer than guessing. It is a report, not medical advice and not a recommendation to use anything. pepmg sells nothing and ships nothing. Listings are price-tracking data, not endorsements.