Compound dossier · evidence, sources, and live market
Glutathione
Antioxidant tripeptide Strong evidence 3 cited studies 60 live vendors
Glutathione (GSH) is a naturally occurring tripeptide composed of glutamate, cysteine, and glycine, notable for the free thiol group on its cysteine residue. In laboratory research it is studied as an antioxidant and redox reference compound, and is often catalogued alongside NAD+ and cosmetic peptides. This index tracks research-use-only (RUO) vendor pricing for Glutathione so labs can compare offerings on a per-milligram basis.
Evidence brief
Glutathione is the body's most abundant intracellular antioxidant tripeptide; the supplement literature studies giving it from outside the body (oral, topical, or intravenous) and is dominated by skin-lightening trials.
first-party prices captured 37m ago
Compare by exact vialThe small sealed glass container a compound ships in. size: 600mg (18 vendors)1200mg (6 vendors)1500mg (45 vendors)
An endogenous antioxidant sold as a dietary supplement; injectable and compounded forms are not FDA-approved as a medicine.Research use only — not medical advice.
These figures are what pepmg still publishes about price: the floor, the middle, the spread and how many sources we track, computed from listings we captured first-party and refreshed on the same schedule as always. We no longer publish the individual listings or the sellers behind them.
Computed from 75 in-stock listings across 60 sources we captured first-party, with bulk vials, blends and statistical outliers excluded so the figures compare like with like. The spread is the highest tracked price divided by the lowest — how much the same milligram varies depending on where you look. The chart is the daily minimum; days we did not capture are left out rather than filled in.
- What the research says about glutathione Strong evidence
Glutathione is the body's most abundant intracellular antioxidant tripeptide; the supplement literature studies giving it from outside the body (oral, topical, or intravenous) and is dominated by skin-lightening trials.
Read the full review →
- Supplementing Glycine and N-Acetylcysteine (GlyNAC) in Older Adults Improves Glutathione Deficiency, Oxidative Stress, Mitochondrial Dysfunction, Inflammation, Physical Function, and Aging Hallmarks: A Randomized Clinical Trial PubMed ↗
Elevated oxidative stress (OxS), mitochondrial dysfunction, and hallmarks of aging are identified as key contributors to aging, but improving/reversing these defects in older adults (OA) is challenging. In prior studies, we identified that…
- Randomized controlled trial of oral glutathione supplementation on body stores of glutathione PubMed ↗
Glutathione (GSH), the most abundant endogenous antioxidant, is a critical regulator of oxidative stress and immune function. While oral GSH has been shown to be bioavailable in laboratory animal models, its efficacy in humans has not been…
- GlyNAC Supplementation Improves Glutathione Deficiency, Oxidative Stress, Mitochondrial Dysfunction, Inflammation, Aging Hallmarks, Metabolic Defects, Muscle Strength, Cognitive Decline, and Body Composition: Implications for Healthy Aging PubMed ↗
Cellular increases in oxidative stress (OxS) and decline in mitochondrial function are identified as key defects in aging, but underlying mechanisms are poorly understood and interventions are lacking. Defects linked to OxS and impaired…
A few representative studies, each summarized on this site with the PubMed record linked beside it — not an endorsement or a claim that any result applies to human use. Read them and judge for yourself. Everything here is research use only.
▸ Why compare $/mg for Glutathione?
Per-mg prices for Glutathione vary across vendors because of differences in fill size, stated HPLC purity, reduced (GSH) versus oxidized (GSSG) form, lyophilization quality, and whether documentation like a COA is included. Comparing normalized $/mg alongside those quality signals helps a researcher distinguish a genuinely cheaper unit from a smaller vial or a lower-spec material.
▸ Reading the COA
For Glutathione, confirm identity by mass spec (monoisotopic mass ~307.08 Da for the reduced form) and check that the COA reports the reduced GSH form rather than oxidized GSSG unless the latter is intended. Look for an HPLC purity figure (commonly 98%+ for research-grade lots) and a stated assay of free thiol content, since air oxidation degrades GSH to GSSG over time. Common concerns are oxidized-form contamination, moisture uptake, and residual solvent or counterion content noted on the certificate.
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▸ Same cluster
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| Melanotan II | $2.11/mg | vs Glutathione → |
| Melanotan I | $2.11/mg | vs Glutathione → |
| Snap-8 | $2.21/mg | vs Glutathione → |
| Argireline | —/mg | |
| AHK-Cu | $0.56/mg | vs Glutathione → |
| Syn-Ake | —/mg | |
| Matrixyl | $10.00/mg | vs Glutathione → |