Tiers name what a vendor publishes, not a verdict on any product's purity or quality.
Lab-verifiable COAs: certificates that open on the testing lab's own site (the seal's ring shows what share of them do).
Third-party COAs: certificates attributed to a third-party lab, which may be hosted only on the vendor's site.
Tiers follow the Vendor Score (90+ and 80–89), which is 87% COA evidence; the numeral in each seal is that score.
Affiliate relationships never affect tiers, selection or order. How the Vendor Score works
Cheapest per vial size
$/mg usually drops as vials get bigger, so the cheapest $/mg overall is often a big vial. Compare inside the size you would actually order. The size with the most listings is 10 mg.
Sermorelin is a synthetic peptide corresponding to the first 29 amino acids of growth-hormone-releasing hormone (GHRH), the fragment characterized in research as the active core of the parent molecule. In laboratory research it is classified as a growth-hormone secretagogue and studied as a GHRH analog that acts on pituitary GHRH receptors in laboratory models. This page tracks research-use-only (RUO) vendor pricing for Sermorelin so researchers can compare cost per milligram across suppliers; it is not intended for human or veterinary use.
Evidence brief
Sermorelin is a growth-hormone-releasing hormone (GHRH) analogue (the first 29 amino acids of GHRH) historically studied as a diagnostic agent and as a treatment in growth-hormone-deficient children.
Formerly FDA-approved (Geref); withdrawn from the US market in 2009 for commercial reasons, not safety. No FDA-approved product today — prescribed only as a compounded drug. Research use only — not medical advice.
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Sermorelin · all tracked vendors · all tracked peptide listings, including out-of-stock products. Prices and stock reflect the last check. Non-comparable products do not enter market rankings. Trust scores measure published evidence, not product safety.
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COACertificate of Analysis: a lab report stating a batch's measured identity and purity.Certificate of Analysis: a lab report stating a batch's measured identity and purity. availability: 61 of 64 tracked sources for Sermorelin publish a COA
— 42 with at least one certificate you can open at the testing lab : Modern Research Peptides (276 at the lab) , Iron Aminos (262 at the lab) , Peptide Partners (149 at the lab) , Eternal Peptides (141 at the lab) , EZ Peptides (136 at the lab) , Happy Peptides (114 at the lab) , Ameano Peptides (108 at the lab) , True Research Labs (96 at the lab) , Feel Good Peptides (90 at the lab) , Amino Science (90 at the lab) , Nationwide Peptides (88 at the lab) , Nexaph (88 at the lab), and 49 more — every one of them is a linked row in the table above. What a COA proves →
Multi-peptide products (e.g. BPC-157 + TB-500). We don't rank these by $/mgPrice divided by the milligrams of active compound — the like-for-like way to compare cost across different vial sizes.Price divided by the milligrams of active compound — the like-for-like way to compare cost across different vial sizes. — a per-milligram figure across different peptides isn't comparable — so they're listed separately by total price and kept out of the headline index above.
Sermorelin is a growth-hormone-releasing hormone (GHRH) analogue (the first 29 amino acids of GHRH) historically studied as a diagnostic agent and as a treatment in growth-hormone-deficient children.
Source-linked reference figures with the population and study context alongside each amount. Study arms are not a starting dose, titration schedule, or personal treatment plan. Label records refer to the named approved medicine, not vendor products.
Dose administered in an uncontrolled clinical treatment study (human, 9 children aged 1.6 to 14 years with growth retardation from chronic renal failure (conservative treatment, dialysis or after transplant); 26 is the group mean (+/- 2.4 SE) daily dose)
a mean of 26 mcg/kg/day, as twice-daily injections, for 3 to 6 months
Named in the source as GHRH (1-29) NH2, Geref (sermorelin) · human · 9 children aged 1.6 to 14 years with growth retardation from chronic renal failure (conservative treatment, dialysis or after transplant); 26 is the group mean (+/- 2.4 SE) daily dose · uncontrolled clinical treatment study · Route reported: subcutaneous
published per unit of bodyweight — pepmg reports it as published and does not convert it to an absolute amount
Dose administered in a randomised-order crossover study of GH response (diagnostic GH stimulation test) (human, 5 women with untreated Cushing's disease and 4 matched healthy women; a diagnostic GH stimulation test, the bolus given once during a galanin infusion and once during a saline infusion)
100 mcg as a single IV bolus, in a diagnostic GH stimulation test
Named in the source as GHRH(1-29)NH2, Geref (sermorelin) · human · 5 women with untreated Cushing's disease and 4 matched healthy women; a diagnostic GH stimulation test, the bolus given once during a galanin infusion and once during a saline infusion · randomised-order crossover study of GH response (diagnostic GH stimulation test) · Route reported: intravenous
Research use only — this reports what an FDA label, a peer-reviewed study or a clinical-trial registry entry published, tied to its species and study context. A trial-registry figure is what a sponsor registered, not a peer-reviewed result. It is not medical advice, not a recommendation to use, and no dose here is generated by pepmg. Any dosing decision is for a qualified professional. Animal-study amounts do not establish a human dose.
Studyspecies not classified BioDrugs · 1999 · PMID 18031173
Sermorelin, a 29 amino acid analogue of human growth hormone-releasing hormone (GHRH), is the shortest synthetic peptide with full biological activity of GHRH. Intravenous and subcutaneous sermorelin specifically stimulate growth hormone…
Reviewspecies not classified Translational andrology and urology · 2020 · PMID 32257855
Male hypogonadism is an increasingly prevalent clinical condition that affects patients' quality of life and overall health. Obesity and metabolic syndrome can both cause and result from hypogonadism. Although testosterone remains the gold…
A few representative studies, each summarized on this site with the PubMed record linked beside it — not an endorsement or a claim that any result applies to human use. Read them and judge for yourself. Everything here is research use only.
Per-milligram prices for Sermorelin vary widely because vials are sold in different peptide masses (commonly 2 mg, 5 mg, or 10 mg), and larger vials usually lower the effective $/mg, while listed weight may reflect net peptide or gross salt/acetate content. Synthesis scale, stated HPLC purity, lyophilization quality, and shipping or cold-chain handling also differ between vendors, so normalizing to $/mg is the only reliable way to compare like with like.
▸ Reading the COA
For Sermorelin, a certificate of analysis should confirm identity by mass spectrometry against the expected monoisotopic mass for the 29-residue GHRH(1-29) sequence (molecular formula around C149H246N44O42S, roughly 3358 Da), and report HPLC purity, with many research suppliers listing 98%+ as a common threshold. Check that the reported net peptide content matches the labeled vial mass, since acetate salt and residual water can inflate gross weight. Watch for truncated or deletion sequences and deamidation byproducts in the HPLC trace, which are typical impurities for peptides of this length. A COA is about verifying the identity and purity of the material, not about any outcome.
▸ FAQ
How is lyophilized Sermorelin typically stored and handled as a research material?
As a lyophilized (freeze-dried) powder, research peptides like Sermorelin are generally kept sealed, desiccated, and protected from light, with cold storage such as -20C or lower commonly cited for longer-term material stability. Repeated warming and exposure to moisture or air can degrade peptide material, so vendors and labs typically minimize freeze-thaw cycles. This is general material-handling and storage context for a research-use-only material only, and is not use guidance.
What is a certificate of analysis (COA) and what should I look for on one for Sermorelin?
A COA is the supplier's analytical document verifying what is in the vial. For Sermorelin, the key items are identity confirmation by mass spectrometry against the expected GHRH(1-29) mass, an HPLC purity value (often reported at 98% or higher), and net peptide content versus the labeled weight. A complete COA also notes the analytical methods and lot number so results can be tied to the specific batch you received.
Why do per-mg prices for Sermorelin differ so much between vendors?
Differences come from vial size (bulkier 5 mg or 10 mg vials usually reduce $/mg versus 2 mg vials), stated purity grade, synthesis scale, and whether the listed mass is net peptide or gross salt-inclusive weight. Cold-chain shipping, lot testing depth, and how much third-party analytical documentation a vendor provides also factor into the price, which is why normalizing to cost per milligram is useful.
All products listed are sold by third-party vendors for laboratory and research use only (RUO). Where an FDA label, a peer-reviewed study or a clinical-trial registry entry has published a dose, pepmg reports it with the source named and the tier labeled (a registry figure is marked trial registry, not peer-reviewed), because that is safer than guessing. It is a report, not medical advice and not a recommendation to use anything. pepmg sells nothing and ships nothing. Listings are price-tracking data, not endorsements.
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