Compound dossier · evidence, sources, and live market
TB-500
Repair peptide Preclinical only 3 cited studies 83 live vendors
TB-500 is a synthetic peptide fragment of thymosin beta-4, studied in research contexts for its role in cell migration and tissue repair mechanisms. Laboratory investigations focus on its potential to modulate actin binding and promote angiogenesis in cellular models.
Evidence brief
"TB-500" is sold as a synthetic peptide related to thymosin β4 (Tβ4); the peer-reviewed literature studies thymosin β4 itself, and it is overwhelmingly preclinical — animal and in-vitro models.
first-party prices captured 37m ago
Compare by exact vialThe small sealed glass container a compound ships in. size: 2mg (3 vendors)5mg (26 vendors)10mg (75 vendors)20mg (4 vendors)
Not approved in the US, EU, or UK. FDA considered TB-500-related substances for the 503A Bulks List at its July 23, 2026 PCAC meeting; committee recommendations are non-binding.Research use only — not medical advice.
Source: FDA Pharmacy Compounding Advisory Committee · July 23–24, 2026checked 2026-07-26
These figures are what pepmg still publishes about price: the floor, the middle, the spread and how many sources we track, computed from listings we captured first-party and refreshed on the same schedule as always. We no longer publish the individual listings or the sellers behind them.
Computed from 111 in-stock listings across 83 sources we captured first-party, with bulk vials, blends and statistical outliers excluded so the figures compare like with like. The spread is the highest tracked price divided by the lowest — how much the same milligram varies depending on where you look. The chart is the daily minimum; days we did not capture are left out rather than filled in.
- What the research says about TB-500 and thymosin β4 Preclinical only
"TB-500" is sold as a synthetic peptide related to thymosin β4 (Tβ4); the peer-reviewed literature studies thymosin β4 itself, and it is overwhelmingly preclinical — animal and in-vitro models.
Read the full review → - Are research peptides safe? What the evidence does and doesn't show Limited evidence
"Are peptides safe?" has no single answer. The compounds sold as research peptides sit at very different points on the evidence scale, from large randomized human trials for a few to animal-only data for many.
Read the full review →
- Thymosin beta-4 denotes new directions towards developing prosperous anti-aging regenerative therapies PubMed ↗
Our dream of defeating the processes of organ damage and aging remains a challenge scientists pursued for hundreds of years. Although the goal is to successfully treat the body as a whole, steps towards regenerating individual organs are…
- Cardioprotection by Thymosin Beta 4 PubMed ↗
Treatment with thymosin beta 4 (Tβ4) reduces infarct volume and preserves cardiac function in preclinical models of cardiac ischemic injury. These effects stem in part from decreased infarct size, but additional benefits are likely due to…
- Thymosin beta 4 as an Alzheimer disease intervention target identified using human brain organoids PubMed ↗
The developmental origin of Alzheimer disease (AD) has been proposed but is arguably debated. Here, we developed cerebral organoids from induced pluripotent stem cells (iPSCs) with mutations in amyloid precursor protein (APP) associated…
A few representative studies, each summarized on this site with the PubMed record linked beside it — not an endorsement or a claim that any result applies to human use. Read them and judge for yourself. Everything here is research use only.
▸ Why compare $/mg for TB-500?
Per-mg prices for TB-500 vary significantly due to differences in synthesis scale, purity grades, and vendor sourcing of raw materials. Comparing prices across verified suppliers helps researchers identify cost-effective options without compromising on quality or lot consistency.
▸ Reading the COA
A valid Certificate of Analysis for TB-500 should confirm peptide identity via mass spectrometry and report purity ≥95% by HPLC. Verify absence of common adulterants such as residual solvents or truncated sequences, and check that the stated mg content matches the delivered quantity.
▸ FAQ
▸ Same cluster
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| ARA-290 | $3.30/mg | vs TB-500 → |
| Pentadeca Arginate | $4.40/mg | vs TB-500 → |