Tiers name what a vendor publishes, not a verdict on any product's purity or quality.
Lab-verifiable COAs: certificates that open on the testing lab's own site (the seal's ring shows what share of them do).
Third-party COAs: certificates attributed to a third-party lab, which may be hosted only on the vendor's site.
Tiers follow the Vendor Score (90+ and 80–89), which is 87% COA evidence; the numeral in each seal is that score.
Affiliate relationships never affect tiers, selection or order. How the Vendor Score works
An oral small-molecule GLP-1 receptor agonist candidate studied in metabolic research.
Evidence brief
Orforglipron is an oral, small-molecule (nonpeptide) GLP-1 receptor agonist in late-stage clinical development for type 2 diabetes and obesity; unlike injectable GLP-1 drugs it is a synthetic non-peptide taken by mouth, and most of the evidence comes from manufacturer-sponsored randomized trials.
Newly FDA-approved: Foundayo (NDA 220934), an oral GLP-1 receptor agonist for chronic weight management in adults with obesity, or overweight with at least one weight-related condition. It has no EMA authorisation; trials continue in the EU and UK, where it remains investigational. Research use only — not medical advice.
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Orforglipron · all tracked vendors · all tracked peptide listings, including out-of-stock products. Prices and stock reflect the last check. Non-comparable products do not enter market rankings. Trust scores measure published evidence, not product safety.
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COACertificate of Analysis: a lab report stating a batch's measured identity and purity.Certificate of Analysis: a lab report stating a batch's measured identity and purity. availability: 9 of 10 tracked sources for Orforglipron publish a COA
— 5 with at least one certificate you can open at the testing lab : My Oasis Labs (73 at the lab) , Swiss Chems (24 at the lab) , Bulk Peptides (9 at the lab) , Happy Peptides (2 at the lab) , Southern Aminos (1 at the lab) , Solution Peptides , PureRawz , Atomik Labz , LiveWell Peptides . What a COA proves →
Orforglipron is an oral, small-molecule (nonpeptide) GLP-1 receptor agonist in late-stage clinical development for type 2 diabetes and obesity; unlike injectable GLP-1 drugs it is a synthetic non-peptide taken by mouth, and most of the evidence comes from manufacturer-sponsored randomized trials.
Source-linked reference figures with the population and study context alongside each amount. Study arms are not a starting dose, titration schedule, or personal treatment plan. Label records refer to the named approved medicine, not vendor products.
Maximum
17.2 mg
Note
The maximum dosage of FOUNDAYO is 9 mg once daily when used concomitantly with a strong CYP3A4 inhibitor
0.8 mg once daily, 2.5 mg once daily, 5.5 mg once daily, 9 mg once daily, 14.5 mg once daily, or 17.2 mg once daily
human · chronic weight management in adults with obesity, or overweight with at least one weight-related condition, alongside a reduced-calorie diet and increased physical activity · FDA label (Foundayo) · Route reported: oral
Dose administered in a phase 3 randomised double-blind trial (ACHIEVE-1) (human, adults with early type 2 diabetes treated with diet and exercise only)
3 mg once daily, 12 mg once daily, or 36 mg once daily
human · adults with early type 2 diabetes treated with diet and exercise only · phase 3 randomised double-blind trial (ACHIEVE-1) · Route reported: oral
Research use only — this reports what an FDA label or a peer-reviewed study published, tied to its species and study context. It is not medical advice, not a recommendation to use, and no dose here is generated by pepmg. Any dosing decision is for a qualified professional. Animal-study amounts do not establish a human dose.
All products listed are sold by third-party vendors for laboratory and research use only (RUO). Where an FDA label or a peer-reviewed study has published a dose, pepmg reports it with the source named, because that is safer than guessing. It is a report, not medical advice and not a recommendation to use anything. pepmg sells nothing and ships nothing. Listings are price-tracking data, not endorsements.
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