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Antioxidant systems and erythrocyte life-span in mammals
Plain-language summary
Paraphrased from the published abstract below — not a verdict on whether anything works.
This review discusses erythrocyte antioxidant systems-superoxide dismutase (SOD), catalase (CAT), reduced glutathione (GSH), glutathione peroxidase (GSH-Px), glutathione S-transferase (GST) and glutathione reductase (GR)-in relation to erythrocyte life-spans across mammalian species. The abstract reports that erythrocyte life-span of different mammals was found to be correlated with levels of SOD, GSH-Px and GSH, and states that reviewed data indicate the erythrocyte life-span of each species is governed by both oxygen radical formation and the intrinsic antioxidant systems.
Abstract
1. Erythrocyte antioxidant systems--superoxide dismutase (SOD), catalase (CAT), reduced glutathione (GSH), glutathione peroxidase (GSH-Px), glutathione S-transferase (GST) and glutathione reductase (GR)--were discussed in relation to life-spans in some mammalian species. 2. The erythrocyte life-span of different mammals was found to be correlated with the levels of SOD, GSH-Px and GSH. 3. Data reviewed indicates that the erythrocyte life-span of each species is governed by both the oxygen radical formation and the efficiency of intrinsic antioxidant systems.
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