Study summary · research use only
Reduced sleep in cats after intraperitoneal injection of delta-sleep-inducing peptide (DSIP)
Plain-language summary
Paraphrased from the published abstract below — not a verdict on whether anything works.
This study in cats examined the effect of intraperitoneally injected delta-sleep-inducing peptide (DSIP) on sleep-wakefulness, using EEG, EMG, and EOG recordings for 10 h after a 30 nmol/kg DSIP or saline control injection. The abstract reports that DSIP reduced total sleep, particularly light slow-wave sleep and REM sleep, and increased REM sleep latency. The authors describe the findings as suggesting that in cats with redundancy sleep, DSIP increased wakefulness at the expense of light slow-wave sleep and produced a specific reduction in REM sleep.
Abstract
The effect of intraperitoneally injected delta-sleep-inducing peptide (DSIP) on sleep-wakefulness in cats was studied using EEG, EMG and EOG recording for 10 h following 30 nmol/kg DSIP or control saline i.p. injections. DSIP reduced the amount of sleep, specifically light slow-wave sleep and REM sleep, and REM sleep latency was increased. The results suggest that in cats with redundancy sleep DSIP increases wakefulness at the cost of light slow-wave sleep, and in addition it has a specific REM-reducing effect.
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