Study summary · research use only
[Comparative analysis of different methods of geroprotective]
Plain-language summary
Paraphrased from the published abstract below — not a verdict on whether anything works.
This monitoring study involved 110 human patients across different age groups, comparing dry carbon dioxide baths, hyperbaric oxygen therapy, therapeutic massage, and oligopeptide preparations (Vezugen and Pinealon, containing lysyl-glutamyl-asparagin and glutamyl-asparagin-arginine complexes) for their reported impact on indicators of biological age. The most pronounced positive impact on biological age indicators was found with combined use of the two oligopeptide complexes. Therapeutic massage and the oligopeptide drugs were reported as having the fewest effects on measured biochemical, immunological, and clinical parameters. Dry carbon dioxide baths and hyperbaric oxygenation showed a positive influence on biological age indicators but were reported to carry a number of limitations and contraindications.
Abstract
In the monitoring process 110 representatives of different age groups held a comparative analysis of the efficacy and safety of several geroprotective techniques, including the use of dry carbon dioxide baths, hyperbaric oxygen therapy, therapeutic massage and receiving Oligopeptide preparations containing complexes lysyl-glutamyl-asparagin and glutamyl-asparagin-arginine (Vezugen and Pinealon). The most pronounced positive impact on indicators of biological age were detected during the combined use of these two Oligopeptide complexes. The most safe from the point of view of influence on a number of biochemical, immunological parameters, clinical condition of the patients were therapeutic massage and Oligopeptide drugs. The use of dry carbon dioxide baths and hyperbaric oxygenation with an undoubtedly positive influence on the indices of biological age has a number of limitations and contraindications regarding its security. У 110 пациентов разного возраста проведен сравнительный анализ эффективности и безопасности нескольких геропротекторных методик, включавших использование сухих углекислых ванн, гипербарической оксигенации, лечебного массажа и приема олигопептидных препаратов, содержащих комплексы лизил-глутамил-аспарагин и глутамил-аспаригил-аргинин (Везуген и Пинеалон). Наиболее отчетливое позитивное влияние на показатели биологического возраста обнаружено при сочетанном применении двух названных олигопептидных комплексов. Наиболее безопасными с точки зрения воздействия на целый ряд биохимических, иммунных показателей и на клиническое состояние пациентов оказались лечебный массаж и олигопептидные препараты. Применение сухих углекислых ванн и гипербарической оксигенации, при несомненно позитивном влиянии на показатели биологического возраста, имеет ряд ограничений и противопоказаний.
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