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Methylene blue treatment in experimental ischemic stroke: a mini review

Study · Brain circulation · 2016 · DOI 10.4103/2394-8108.178548 · PMID 27042692

Plain-language summary

Paraphrased from the published abstract below — not a verdict on whether anything works.

This mini review discusses methylene blue, a drug with a long history of use in humans for treating methemoglobinemia and cyanide poisoning, in the context of studies on experimental stroke models (species not specified). The abstract states methylene blue has recently been shown to have neuroprotective effects in neurodegenerative disease and brain injury models, and that the goal of the paper is to review studies of methylene blue in experimental stroke models.

Abstract

Stroke is a leading cause of death and long-term disability. Methylene blue, a drug grandfathered by the Food and Drug Administration with a long history of safe usage in humans for treating methemoglobinemia and cyanide poisoning, has recently been shown to be neuroprotective in neurodegenerative diseases and brain injuries. The goal of this paper is to review studies on methylene blue in experimental stroke models.

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