Study summary · research use only
[Influence of peptides from pineal gland on thymus function at aging]
Plain-language summary
Paraphrased from the published abstract below — not a verdict on whether anything works.
This review discusses interactions between the thymus and pineal gland during their involution, summarizing data on effects of thymus peptides on the pineal gland and pineal peptides on the thymus in the context of aging (species not specified). The review's analysis suggested pineal peptides (epithalamin, epitalon) had a more pronounced geroprotective effect on thymus involution compared with the geroprotective effect of thymic peptides (thymalin, thymogen) on pineal gland involution. The authors described the key mechanism as immunoendocrine cooperation realized through activation of transcription of various proteins.
Abstract
The interference between thymus and pineal gland during their involution is considered in this review. The research data about influence of thymus peptides on pineal gland and pineal peptides on thymus is summarized. Analysis of these data showed that pineal peptides (epithalamin, epitalon) had more effective geroprotective effect on thymus involution in comparison with geroprotective effect of thymic peptides (thymalin, thymogen) on involution of pineal gland. The key mechanisms of pineal peptides effect on thymus dystrophy is immunoendocrine cooperation, which is realized as transcription's activation of various proteins.
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