Study summary · research use only
Effect of Ala-Glu-Asp-Gly peptide on life span and development of spontaneous tumors in female rats exposed to different illumination regimes
Plain-language summary
Paraphrased from the published abstract below — not a verdict on whether anything works.
In this rat study, the authors examined Ala-Glu-Asp-Gly peptide (Epithalon) on life span and spontaneous tumors in female rats exposed to standard, natural (North-Western Russia), or constant illumination. The abstract reports that mean life span decreased by 13.5 and 25.5% under constant and natural illumination and maximum life span by 9 and 7 months, respectively, with more rapid tumor development than under the standard regimen. Epithalon (0.1 microg daily 5 times a week from age 4 months) did not change life span under the standard regimen, but under natural and constant light prolonged maximum life span by 95 and 24 days and the mean life span of the last 10% of rats by 137 and 43 days, respectively. Epithalon significantly inhibited spontaneous tumor development in rats under natural light.
Abstract
The effects of Ala-Glu-Asp-Gly peptide (Epithalon) on the life span and development of spontaneous tumors were studied in female rats exposed to standard, natural for North-Western Russia, and constant illumination. The mean life span of animals exposed to constant or natural illumination decreased by 13.5 and 25.5%, the maximum by 9 and 7 months, respectively, and spontaneous tumors developed much more rapidly than in animals living under conditions of the standard light regimen. Epithalon (0.1 microg daily 5 times a week from the age of 4 months) did not change the life span of rats living under conditions of standard day/night regimen, while in rats exposed to the natural and constant light it promoted prolongation of the maximum life span by 95 and 24 days, respectively. Epithalon prolonged the mean life span of the last 10% of rats exposed to natural and constant illumination, treated with Epithalon, by 137 and 43 days, respectively. This peptide exhibited virtually no effect on the development of spontaneous tumors in rats exposed to standard and constant illumination, but significantly inhibited their development in rats exposed to natural light.
pepmg summarizes the peer-reviewed literature and links to every source — it sells nothing, ships nothing, and gives no medical, dosing, or human-use guidance. Don't just trust this summary: follow the citation to its source and read it yourself. Research use only.