Study summary · research use only
[Comparison of anticoagulant effects of regulatory proline-containing oligopeptides. Specificity of glyprolines, semax, and selank and potential of their practical application]
Plain-language summary
Paraphrased from the published abstract below — not a verdict on whether anything works.
This review article compares reported anticoagulant effects of regulatory proline-containing oligopeptides, including glyprolines, Semax, and Selank. The authors discuss the relevance of regulatory peptides to blood coagulation, noting that such peptides are widespread in animal and plant tissues, that peptide structure relates to function, and that natural and synthetic peptides are used in medicine to modify hemostatic factors. They note that many peptide inhibitors of primary and plasma hemostasis, described as potentiating anticoagulant effects in the body, have been reported. The piece is a narrative overview; species are not specified.
Abstract
Experimental and theoretical demonstration of different effect of certain regulatory peptides (RPs) on blood coagulation is available. The problem of the role of RPs in hemostatic processes becomes particularly significant since, first, the peptides are widespread in nature both in animal and plant tissues, second, there is a relationship between the peptide structure and function and, third, both natural and synthetic peptides are used in practical medicine to correct functions of some factors of the hemostatic system. Many peptide inhibitors of the primary and plasma hemostasis potentiating anticoagulant effects in the body have been described.
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