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Study summary · research use only

Effect of Vilon and Epithalon on glucose and glycine absorption in various regions of small intestine in aged rats

Study · animal · Bulletin of experimental biology and medicine · 2002 · DOI 10.1023/a:1019878224754 · PMID 12420071

Plain-language summary

Paraphrased from the published abstract below — not a verdict on whether anything works.

This study in aged rats examined oral administration of Vilon (Lys-Glu) and Epithalon (Ala-Glu-Asp-Gly) for 1 month and their association with glucose and glycine transport across small intestine regions. Vilon was associated with increased passive glucose accumulation in the distal small intestine and active glucose accumulation in the medial small intestine. Epithalon was associated with increased passive glucose accumulation in the medial region and active glucose accumulation in the proximal and distal regions. Glycine absorption increased only in the proximal segment with Epithalon.

Abstract

Vilon (Lys-Glu) and Epithalon (Ala-Glu-Asp-Gly) administered orally for 1 month improved transport characteristics of the small intestine in aged rats. Vilon enhanced passive glucose accumulation in the serous fluid in inverted sac made from the distal region of the small intestine, while Epithalon enhanced this process in the medial region. Vilon stimulated active glucose accumulation in the serous sac of the medial small intestine, Epithalon - in the proximal and distal small intestinal segments. Glycine absorption increased only in the proximal intestinal segment under the effect of Epithalon.

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