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Tissue-specific effects of peptides

Study · animal · Bulletin of experimental biology and medicine · 2001 · DOI 10.1023/a:1013058701974 · PMID 11713572

Plain-language summary

Paraphrased from the published abstract below — not a verdict on whether anything works.

This rat study examined the synthetic peptides Cortagen, Epithalon, Livagen, and Vilon in organotypic cultures of explants from rat brain cortex, subcortical structures, liver, and thymus respectively. The authors report each peptide stimulated growth of the explant type matching the tissue from which its corresponding cytomedin (peptide complex) had originally been chemically synthesized, describing this as a tissue-specific pattern of action. Species: rats.

Abstract

Synthetic peptides (cytogens) Cortagen, Epithalon, Livagen, and Vilon stimulated the growth of explants from rat brain cortex, subcortical structures, liver, and thymus, respectively, in organotypic cultures. These peptides produced tissue-specific effects: they stimulated the growth of explants from tissues, whose cytomedins (peptide complexes) were used for chemical synthesis.

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