Study summary · research use only
Effects of peptides on generation of reactive oxygen species in subcellular fractions of Drosophila melanogaster
Plain-language summary
Paraphrased from the published abstract below — not a verdict on whether anything works.
This study in Drosophila melanogaster (a highly inbred HA(+) line) examined effects of the peptides Epithalon (Ala-Glu-Asp-Gly) and Vilon (Lys-Glu) on free radical processes in subcellular fractions. The authors report Vilon inhibited generation of reactive oxygen species in mitochondria but stimulated this process in the cytosol. They also report sex- and age-related differences in reactive oxygen species generation and in cytosol antioxidant activity. Species: Drosophila melanogaster (fruit fly).
Abstract
We studied the effects of Epithalon (Ala-Glu-Asp-Gly) and Vilon (Lys-Glu) on free radical processes in highly inbred HA(+)line of Drosophila melanogaster. Vilon inhibited generation of reactive oxygen species in mitochondria, but stimulated this process in the cytosol. We found sex- and age-related differences in the generation of reactive oxygen species and cytosol antioxidant activity.
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