Study summary · research use only
[Treatment with thymogen and myelopid of patients with bronchial asthma]
Plain-language summary
Paraphrased from the published abstract below — not a verdict on whether anything works.
The abstract provided does not match the title; it reports a study of alpha-tocopherol acetate and nicotinamide on lipid peroxidation and antioxidant enzyme defense in red cell membranes of 61 patients with new-onset insulin-dependent diabetes mellitus. Lipid peroxidation products were reported in excessive quantities while cell antioxidant enzymes were decreased. The authors state that combining tocopherol with nicotinamide alongside conventional insulin therapy was associated with normalization of lipid peroxidation and antioxidant enzyme defense and with beta-cell function, and describe introducing antioxidant treatment early in the disease.
Abstract
The authors studied the effect of alpha-tocopherol acetate and nicotinamide on lipid peroxidation and antioxidant enzyme defense (AED) in red cell membranes of 61 patients with new-onset insulin-dependent diabetes mellitus. Lipid peroxidation products were found in excessive quantities, whereas enzymes of the cell antioxidant defense were on the decrease. Combination of tocopherol with nicotinamide as adjuvants to conventional insulin therapy promoted normalization of lipid peroxidation and AED, improving beta-cell function. It is believed justified to introduce antioxidant treatment early in the disease onset to prevent toxic damage to beta-cells and vascular endothelium induced by lipid peroxidation products.
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