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Study summary · research use only

[Changes of immune and non-specific reactivity in patients with chronic suppurative obstructive bronchitis in comprehensive treatment with thymogen]

Clinical trial · human · Problemy tuberkuleza · 1994 · PMID 7984617

Plain-language summary

Paraphrased from the published abstract below — not a verdict on whether anything works.

This report describes 33 patients with chronic pyoobstructive bronchitis who had immunological disorders (T-cell and other) and altered nonspecific responsiveness. The abstract reports that use of thymogen in multi-modality treatment was associated with normalization of T-cell immunity parameters (increases in E-rosette formation, blast cell transformation responses to phytohemagglutinin, Tx/Tc ratio) and nonspecific responsiveness parameters (C3c, NBT-test, natural killers), which the authors associate with a higher clinical outcome.

Abstract

A total of 33 patients with chronic pyoobstructive bronchitis with immunological disorders (of T-cell and other links) and nonspecific responsiveness. The use of thymogen in multi-modality treatment contributed to normalization of T-cell immunity (increases in E-rosette formation, responses of blast cell transformation to phytohemagglutinin, Tx/Tc ratio), as well as nonspecific responsiveness parameters (C3c, NBT-test, natural killers), resulting in higher clinical efficacy.

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