Study summary · research use only
Vasoactive Intestinal Polypeptide Secreting MS Neuroblastoma
Plain-language summary
Paraphrased from the published abstract below — not a verdict on whether anything works.
This case report describes a human pediatric case: a 17-month-old child diagnosed with MS-stage neuroblastoma and chronic diarrhea attributed to elevated vasoactive intestinal peptide (VIP) levels. The authors describe this as a rare combination not previously reported in the literature. The child underwent exploratory laparotomy with excision of the tumor, after which VIP levels declined significantly and symptoms resolved.
Abstract
We present a rare case of a 17-month-old child diagnosed with MS-stage neuroblastoma and associated chronic diarrhea due to elevated vasoactive intestinal peptide (VIP) levels. The unusual occurrence of a VIP-secreting tumor in a patient with MS neuroblastoma is a rare combination, not previously reported in the literature. The patient underwent exploratory laparotomy and excision of the tumor, leading to a significant decline in VIP levels and resolution of symptoms.
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