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Seasonal Influence on the Impact of Human Chorionic Gonadotropin (hCG) on Testicular Haemodynamics and Hormonal Responses in Canines: A Comparative Study
Plain-language summary
Paraphrased from the published abstract below — not a verdict on whether anything works.
This comparative study in male dogs examined seasonal variation in the response to human chorionic gonadotropin (hCG) treatment, focusing on testicular blood flow and plasma testosterone and oestrogen. Using colour Doppler ultrasonography across spring, summer, fall, and winter, testicular haemodynamics and hormone levels were measured at multiple time points after hCG injection. The response to hCG was reported to vary by season, with significant variations in both blood flow and hormone levels, and a significant negative relationship between testicular blood flow and testosterone levels, particularly in spring and summer. The authors suggest seasonality should be considered when administering hCG for reproductive treatments in dogs.
Abstract
Human chorionic gonadotropin (hCG) is widely used to treat reproductive dysfunction by enhancing testicular blood flow and stimulating hormonal activity. This study investigates the seasonal variations in the response to hCG treatment in male dogs, focusing on its effects on testicular blood flow and plasma concentrations of testosterone and oestrogen. Conducted across different seasons (spring, summer, fall and winter), the study utilised colour Doppler ultrasonography to measure testicular haemodynamics and analysed hormonal levels at multiple time points post-hCG injection. The findings revealed that the response to hCG is modulated by seasonal factors, with significant variations in both blood flow and hormone levels. A significant negative relationship was indicated between testicular blood flow and testosterone levels, particularly during spring and summer. These results suggest that seasonality should be considered when administering hCG for reproductive treatments in canines.
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