Study summary · research use only
INDIVIDUAL ARTICLE: Real-World Clinical Experience With a Neuro-Peptide Serum in Combination With Botulinum Toxin Type-A Injections
Plain-language summary
Paraphrased from the published abstract below — not a verdict on whether anything works.
This article describes real-world clinical experience in human dermatology patients combining a topical neuro-peptide serum, containing 2% acetyl hexapeptide-8, 2% dipeptide diaminobutyroyl, 5% polyhydroxy acids, 5% niacinamide, and 1% laminaria extract, with botulinum toxin type-A (BTX-A) injections. Cases from 5 dermatologists and 2 surgeons using twice-daily serum application alongside BTX-A are reported. The abstract describes the serum as targeting 9 skin biomarkers related to wrinkles and skin brightness, and reports that in these real-world cases, the combination was associated with improved radiance and reduced fine lines and wrinkles across diverse patients.
Abstract
We evaluated real-life experiences of a topical neuro-peptide serum containing 2% acetyl hexapeptide-8, 2% dipeptide diaminobutyroyl, 5% polyhydroxy acids (PHA), 5% niacinamide, and 1% laminaria extract (topical neuro-peptide serum [TNP-serum]). The TNP-serum works synergistically by stimulating 9 key skin biomarkers to reduce wrinkles and produce a skin-brightening effect. Here, we highlight the real-life experiences of 5 dermatologists and 2 surgeons, using an integrated skincare regimen consisting of botulinum toxin type-A (BTX-A) injection in conjunction with twice daily TNP-serum. Real-world cases provide evidence for combination treatments that may be used in cosmetic dermatology to improve patient outcomes and satisfaction. TNP-serum appears to complement BTX-A injections to improve radiance, reduce fine lines, and reduce wrinkles in diverse patients. Incorporating TNP-serum into integrated skincare regimens may offer an additive effect to BTX-A injections and, ultimately, optimize patient results. J Drugs Dermatol. 2024;23:11(Suppl 2):s3-14.
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