Study summary · research use only
Afamelanotide
Plain-language summary
Paraphrased from the published abstract below — not a verdict on whether anything works.
This entry describes afamelanotide, a melanocortin-1 receptor agonist that stimulates melanin production in the skin, used in human patients with erythropoietic protoporphyria and X-linked protoporphyria to reduce pain and itching from light exposure. The text states afamelanotide has not been linked to serum aminotransferase elevations during therapy or to instances of idiosyncratic acute liver injury with symptoms and jaundice.
Abstract
Afamelanotide is a melanocortin-1 receptor agonist that stimulates melanin production in the skin and is used to decrease pain and itching from light exposure in patients with erythropoietic protoporphyria and X-linked protoporphyria. Afamelanotide has not been linked to serum aminotransferase elevations during therapy nor to instances of idiosyncratic acute liver injury with symptoms and jaundice.
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