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Study summary · research use only

[Age features of bioregulatory therapy of dental diseases.]

Study · human · Advances in gerontology = Uspekhi gerontologii · 2020 · PMID 32362097

Plain-language summary

Paraphrased from the published abstract below — not a verdict on whether anything works.

This review (species not specified; human dental patients discussed) describes the use of peptide bioregulators of cell homeostasis in various dental diseases and pathology of the maxillofacial region. It covers immunopharmacological effects and clinical use of peptide thymomimetics (thymalin, thymogen, vilon, epithalamin, cortexin) and peptide bioregulators from cartilaginous and other tissues (sigumir, chondrolux) in trauma and inflammatory conditions of the oral cavity and maxillofacial region, with particular attention to their use in dental disease treatment in elderly patients.

Abstract

The article presents data on the use of peptide bioregulators of cell homeostasis and the protective functions of the body in various dental diseases and pathology of organs and tissues of the maxillofacial region. Issues related to the immunopharmacological effect and clinical use of natural and synthetic peptide thymomimetics (thymalin, thymogen, vilon, epithalamin, cortexin) and peptide bioregulators from cartilaginous (sigumir, chondrolux) and other tissues in case of trauma, as well as inflammatory, inflammatory and other pathological processes of tissues of the oral cavity and maxillofacial region. Particular attention is paid to their use in the complex treatment of dental diseases in the elderly. В статье представлены данные по применению пептидных биорегуляторов клеточного гомеостаза и защитных функций организма при различных стоматологических заболеваниях и патологии органов и тканей челюстно-лицевой области. Рассмотрены вопросы, связанные с иммунофармакологическим действием и эффективностью клинического применения природных и синтетических пептидных тимомиметиков (Тималина, Тимогена, Вилона, Эпиталамина, Кортексина) и пептидных биорегуляторов из хрящевой (сигумир, хондролюкс) и других тканей при травме, а также воспалительных, дистрофических, онкологических и других патологических процессах тканей полости рта и челюстно-лицевой области. Особое внимание уделено их использованию в комплексном лечении стоматологических заболеваний у лиц пожилого и старческого возраста.

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