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Study summary · research use only

[The use of acetyl-L-carnitine in gerontological practice]

Review · human · Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova · 2017 · DOI 10.17116/jnevro20171176281-86 · PMID 28980618

Plain-language summary

Paraphrased from the published abstract below — not a verdict on whether anything works.

This is a narrative review of published literature on acetyl-L-carnitine (ALC) use in gerontological practice, describing its biochemical activity, mechanism of action, and profile, and discussing the possibility of combining nicergoline with other drugs. The review analyzes results of preclinical and clinical studies on ALC application in world medical practice. The authors describe ALC as having a broad spectrum of activity, based on their analysis of the literature.

Abstract

An analysis of literature data on the acetyl-L-carnitine treatment in gerontological practice is performed. This review describes the range of biochemical activity and mechanism of action of the drug. The profile and specificity of acetyl-L-carnitine action and the possibility of combining nicergoline with other drugs is discussed. The results of preclinical and clinical studies on the application of acetyl-L-carnitine in the world medical practice are analyzed. The analysis of the studies demonstrates the high efficacy and a broad spectrum of acetyl-L-carnitine treatment. Проведен анализ данных литературы об эффективности и безопасности применения ацетил-L-карнитина (АЛК) в геронтологической практике, описан спектр биохимической активности и механизм действия. Обсуждаются профиль и специфичность действия АЛК, а также возможность его сочетания с другими препаратами. Анализируются результаты преклинических и клинических исследований применения АЛК в мировой медицинской практике. Продемонстрированы высокая эффективность и широкий спектр действия АЛК.

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