Study summary · research use only
Human Chorionic Gonadotropin: The Pregnancy Hormone and More
Plain-language summary
Paraphrased from the published abstract below — not a verdict on whether anything works.
This review article examines published research and international literature on human chorionic gonadotropin (hCG) and its role in reproduction, along with newer non-traditional theories about its functions. The abstract reports that hCG and its receptor, LH/CGR, are expressed at multiple sites in the reproductive tract, in both gonadal and extra-gonadal tissues, and are described as involved in oocyte maturation, fertilization, implantation, and early embryo development. The authors also describe a potential role for hCG as an anti-rejection agent in solid organ transplantation. The review calls for further research into the functions of hCG and LH/CGR to clarify their clinical potential. No specific study population, species, or numerical data are given in the abstract.
Abstract
To thoroughly review the uses of human chorionic gonadotropin (hCG) related to the process of reproduction and also assess new, non-traditional theories. Review of the international literature and research studies. hCG and its receptor, LH/CGR, are expressed in numerous sites of the reproductive tract, both in gonadal and extra-goanadal tissues, promoting oocyte maturation, fertilization, implantation and early embryo development. Moreover, hCG seems to have a potential role as an anti-rejection agent in solid organ transplantation. Future research needs to focus extensively on the functions of hCG and its receptor LH/CGR, in an effort to reveal known, as well as unknown clinical potentials.
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