Study summary · research use only
Mangiferin modulation of metabolism and metabolic syndrome
Plain-language summary
Paraphrased from the published abstract below — not a verdict on whether anything works.
This review discusses biological and pharmacological effects of mangiferin (MGF), the predominant constituent of Mangifera indica (mango) extracts, in relation to metabolic disorders such as obesity and diabetes. It reports that MGF has documented antioxidant and anti-inflammatory effects and describes recent studies indicating it modulates biological processes involved in carbohydrate and lipid metabolism. The abstract states MGF has been reported to affect metabolic abnormalities and disorders in animal models and in humans, and the review focuses on summarizing these reported biological and pharmacological effects of MGF on metabolism and metabolic disorders.
Abstract
The recent emergence of a worldwide epidemic of metabolic disorders, such as obesity and diabetes, demands effective strategy to develop nutraceuticals or pharmaceuticals to halt this trend. Natural products have long been and continue to be an attractive source of nutritional and pharmacological therapeutics. One such natural product is mangiferin (MGF), the predominant constituent of extracts of the mango plant Mangifera indica L. Reports on biological and pharmacological effects of MGF increased exponentially in recent years. MGF has documented antioxidant and anti-inflammatory effects. Recent studies indicate that it modulates multiple biological processes involved in metabolism of carbohydrates and lipids. MGF has been shown to improve metabolic abnormalities and disorders in animal models and humans. This review focuses on the recently reported biological and pharmacological effects of MGF on metabolism and metabolic disorders. © 2016 BioFactors, 42(5):492-503, 2016.
pepmg summarizes the peer-reviewed literature and links to every source — it sells nothing, ships nothing, and gives no medical, dosing, or human-use guidance. Don't just trust this summary: follow the citation to its source and read it yourself. Research use only.