Study summary · research use only
Chrono- and Immunocorrection of Inflammatory Disorders of Internal Reproductive Organs in Women of Reproductive Age
Plain-language summary
Paraphrased from the published abstract below — not a verdict on whether anything works.
In this study, the authors compared immunomodulators in treating patients with chronic salpingitis and oophoritis, with or without changes in succinate dehydrogenase (SDH) activity in blood lymphocytes on incubation with the drug. The abstract reports diurnal variations in individual SDH reaction to thymalin or ridostin, and that in women receiving ridostin or thymalin during an SDH reaction, clinical, laboratory and immunological parameters improved in most patients, while less improvement was seen when drugs were given without an SDH reaction. The authors suggest timing drug application to the presence of the SDH reaction in immunocompetent cells to select the optimal regimen for each case.
Abstract
We compared the effectiveness of immunomodulators used in the treatment of patients with chronic salpingitis and oophoritis with or without changes in succinate dehydrogenase (SDH) activity in blood lymphocytes at incubation with the drug. Diurnal variations in individual reaction of SDH in blood lymphocytes to thymalin or ridostin were revealed. In the groups of women receiving ridostin or thymalin during the reaction of lymphocyte SDH to it, improvement of clinical laboratory and immunological parameters was observed in the majority of the patients and no effect was found in a lesser group of patients than in the groups treated with drugs during the absence of lymphocyte SDH reaction thereto. The timing of the presence of SDH reaction to drugs in the immunocompetent cells makes it possible to set the optimal daily regime of their application and to select a drug that would be most effective in each particular case.
pepmg summarizes the peer-reviewed literature and links to every source — it sells nothing, ships nothing, and gives no medical, dosing, or human-use guidance. Don't just trust this summary: follow the citation to its source and read it yourself. Research use only.