Study summary · research use only
Comment on "a peptidomimetic targeting white fat causes weight loss and improved insulin resistance in obese monkeys"
Plain-language summary
Paraphrased from the published abstract below — not a verdict on whether anything works.
This commentary responds to a study reporting that the peptidomimetic adipotide reduces weight in obese monkeys by inducing apoptosis of blood vessels surrounding white adipose tissue. The commentary suggests that the reported weight loss may instead reflect a direct effect of adipotide on food consumption rather than the proposed vascular apoptosis mechanism.
Abstract
A study reporting that a peptidomimetic adipotide reduces weight loss in obese monkeys by inducing apoptosis of blood vessels surrounding white adipose tissue may instead reflect a direct effect of adipotide on food consumption.
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