Study summary · research use only
[Application thymogen for preoperative preparation of elderly patients with tumor processes in abdominal cavity]
Plain-language summary
Paraphrased from the published abstract below — not a verdict on whether anything works.
This double-blind, randomized, placebo-controlled study evaluated Thymogen preparation for preoperative preparation of elderly human patients undergoing surgery for solid tumors in the abdominal cavity and retroperitoneal space. Thymogen was administered by intranasal instillation of 100 mg once a day for 7 days before surgery, with an isotonic sodium chloride solution used for the placebo group on the same schedule. The study reports that preoperative Thymogen use was associated with restoration of structural and functional parameters of cellular immunity, and that immunomodulatory therapy resulted in a significant decrease in the number and range of postoperative complications and a shortened postoperative period.
Abstract
A double-blind, randomized, placebo-controlled study of the efficacy of Thymogen preparation for elderly patients for surgery on the solid tumors in abdominal cavity and retroperitoneal space was carried out. The drug has been administered by intranasal instillation of 100 mg once a day for 7 days before surgery. The isotonic sodium chloride solution for the placebo group in the same scheme was used. The preoperative use of Thymogen proved to be useful to restore the structural and functional parameters of cellular immunity. Immunomodulatory therapy resulted in the significant decrease in the number and range of post-operative complications and the shorting of the postoperative period.
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