Effect of pancragen on blood glucose level, capillary permeability and adhesion in rats with experimental diabetes mellitus

Plain-language summary

Paraphrased from the published abstract below — not a verdict on whether anything works.

In this rat study, the authors examined the tetrapeptide pancragen (Lys-Glu-Asp-Trp-NH2) on blood glucose and on permeability and adhesion of mesenteric capillaries in Wistar rats with streptozotocin-induced diabetes mellitus. The abstract reports that oral pancragen produced what the authors describe as a pronounced hypoglycemic effect during treatment, and that intramuscular pancragen normalized the adhesion of mesenteric capillary endothelium but did not modify capillary permeability. The authors interpret the results as indicating homeostatic and endothelioprotective effects of pancragen during the early period of diabetes mellitus. No numerical figures were provided in the abstract.