Study summary · research use only
Preparation and stability of cosmetic formulations with an anti-aging peptide
Plain-language summary
Paraphrased from the published abstract below — not a verdict on whether anything works.
This article reviews the physiological basis and mechanism of action of the cosmetic ingredient acetyl hexapeptide-8 (Argireline) and describes preparation of formulations, with no living-organism testing reported. The authors state that skin wrinkling with age involves genetic, constitutional, hormonal, nutritional, and environmental factors as well as repeated facial movements. They prepared two formulations: an emulsion with an external aqueous phase for normal to dry skin and a gel for oily skin. Laboratory analyses, rheology tests, and in vitro release assays were used to evaluate the stability of these cosmetic formulations. No efficacy or clinical outcomes were reported in the abstract.
Abstract
Wrinkling of the skin is the most obvious sign of deterioration of the human body with age. This process involves a number of genetic, constitutional, hormonal, nutritional, and environmental factors, in addition to the influence of frequently repeated facial movements during laughing, smoking, etc. This article reviews the physiological basis and mechanism of action of the active cosmetic ingredient acetyl hexapeptide-8 (Argireline). We prepared two formulations: an emulsion with an external aqueous phase for normal to dry skin, and a gel for oily skin. Laboratory analyses, rheology tests and in vitro release assays were used to evaluate the stability of these formulations for cosmetic treatment.
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