Study summary · research use only
[The tissue-specific effect of synthetic peptides-biologic regulators in organotypic tissues culture in young and old rats]
Plain-language summary
Paraphrased from the published abstract below — not a verdict on whether anything works.
In this rat study, the authors examined synthetic peptides, cardiogen, bronchogen, prostamax, and pancragen, on organotypic tissue cultures of heart, lung, prostate, and pancreas explants from young (3-week-old) and aged (18-month-old) rats. They report that at a concentration of 0.05 ng/ml the peptides showed a stimulating action in the corresponding tissue cultures compared with control explants across all rat groups. The authors suggest these bioregulatory peptides could be used to stimulate reparative processes in the appropriate tissues during ageing.
Abstract
The synthetic peptides--cardiogen, bronchogen, prostamax and pancragen were used to investigate their effect on organotypic tissue culture of explants from heart, lungs, prostatic gland and pancreas of young (3-week old) and aged (18-month old) rats. The peptide effective concentration of 0.05 ng/ml showed a stimulating effect in appropriate tissue cultures as compared to the control explants in all groups of rats. So these bioregulatory peptides can be used in clinic practice for the stimulation of reparative processes in the appropriate tissues while ageing.
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