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Effect of the dipeptide vilon on activity of digestive enzyme in rats of various ages

Study · animal · Bulletin of experimental biology and medicine · 2001 · DOI 10.1023/a:1012319122696 · PMID 11586413

Plain-language summary

Paraphrased from the published abstract below — not a verdict on whether anything works.

This rat study (male and female Wistar rats aged 3 and 11 months) examined effects of oral administration of the dipeptide Vilon (Lys-Glu) on digestive enzyme activity, including invertase, maltase, alkaline phosphatase, and amino- and dipeptidases, across sections of the gastrointestinal tract. The authors report enzyme activity changed with treatment, with the largest increases seen in 11-month-old animals, narrowing the differences between the two age groups. The authors describe the changes in digestive enzyme activity during aging as positive. Species: rats.

Abstract

Peroral administration of Vilon (Lys-Glu) to male and female Wistar rats aging 3 and 11 months changed activity of digestive enzymes (invertase, maltase, alkaline phosphatase, and amino- and dipeptidases) in various portions of the gastrointestinal tract. The increase in enzyme activity was most pronounced in 11-month-old animals, which diminished differences between rats of various ages. Our results indicate that Vilon produces positive effects on digestive enzyme activity during aging.

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