Study summary · research use only
[Effect of pineal peptides on neuroendocrine system after pinealectomy]
Plain-language summary
Paraphrased from the published abstract below — not a verdict on whether anything works.
This rat study (albino rats) examined how removal of the pineal gland affects gastric endocrine cells and thyroid C-cells, using immunohistological and morphometric methods. The authors report that pinealectomy led to structural and functional changes in these cell populations, and that injection of the pineal peptides epithalone and epithalamine reversed these changes. The authors state their belief that epithalone has higher biological activity than epithalamine. Species: rats.
Abstract
Removal of the pineal gland leads to structural and functional rearrangement of gastric endocrine cells and thyroid C-cells in albino rats, as was shown by immunohistological methods and morphometry. Injection of pineal peptides epithalone and epithalamine eliminated these changes. Biological activity of epithalone is believed to be higher than that of epithalamine.
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