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Study summary · research use only

Effect of tetrapeptide cortagen on regeneration of sciatic nerve

Study · animal · Bulletin of experimental biology and medicine · 2000 · PMID 11276314

Plain-language summary

Paraphrased from the published abstract below — not a verdict on whether anything works.

In this rat study, researchers examined intramuscular cortagen, a tetrapeptide, on regeneration of the sciatic nerve after transsection and suturing. Rats received cortagen (10 microg/kg) for 10 days following surgery. The authors report that cortagen treatment was associated with an increase in the growth rate and conduction velocity of regenerating nerve fibers by 27% and 40%, respectively, compared with untreated animals.

Abstract

Intramuscular injection of 10 microg/kg cortagen to rats during 10 days after transsection and suturing of the sciatic nerve increased the growth rate and conduction velocity in the regenerating nerve fibers by 27% and 40%, respectively.

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