Study summary · research use only
Effect of vilon on biological age and lifespan in mice
Plain-language summary
Paraphrased from the published abstract below — not a verdict on whether anything works.
In this mouse study, female CBA mice received subcutaneous vilon (Lys-Glu) starting from the 6th month of life. Vilon administration was associated with increased physical activity and endurance, decreased body temperature, longer lifespan, and prevention of spontaneous neoplasm development in these mice. The authors report no effect of vilon on age-related changes in estrous function or free radical processes, and no unfavorable effects on animal development with long-term administration. The authors describe these findings as supporting further use of vilon for geroprotection and prevention of age-related pathology, without reporting evidence of harm from chronic administration.
Abstract
Subcutaneous administration of vilon (Lys-Glu) to female CBA mice starting from the 6th month of life increased physical activity and endurance, decreased body temperature, prolonged the lifespan, and prevented the development of spontaneous neoplasms. Vilon had no effect on age-related changes of estrous function and free radical processes. Long-term administration of vilon caused no unfavourable effects on animal development. The obtained results show safety of chronic vilon administration and allow to use this preparation for geroprotection and prophylaxis of age pathology.
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